Incidence, Etiology and Risk Factors Associated with Mortality of Nosocomial Candidemia in a Tertiary Care Hospital in Istanbul, Turkey

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dc.authorscopusid6602163658
dc.authorscopusid9845356900
dc.authorscopusid25622697400
dc.authorscopusid6506606196
dc.authorscopusid25622805300
dc.authorscopusid6506778903
dc.authorscopusid56868762000
dc.authorwosidInan, Asuman/D-5679-2014
dc.contributor.authorErdem, İlknur
dc.contributor.authorOğuzoğlu, Naz
dc.contributor.authorEngin, Derya Öztürk
dc.contributor.authorÖzgültekin, Asu
dc.contributor.authorİnan, Asuman Şengöz
dc.contributor.authorCeran, Nurgül
dc.contributor.authorGöktaş, Paşa
dc.date.accessioned2022-05-11T14:37:21Z
dc.date.available2022-05-11T14:37:21Z
dc.date.issued2010
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları Ana Bilim Dalı
dc.description.abstractObjective: The aim of this study was to determine the incidence, etiology and risk factors for mortality of patients with nosocomial candidemia. Subjects and Methods: This observational study was performed at Haydarpasa Numune Training and Research Hospital, a tertiary care hospital with 750 beds, between the years 2004 and 2007. Fifty defined cases with a nosocomial bloodstream infection caused by Candida species were included in the study. All demographic, microbiological and clinical records for each patient were collected using a standardized form. Blood culture was performed by automated blood culture system, and those samples positive for yeast were subcultured on Sabouraud agar. Results: The mean incidence density of nosocomial candidemia was 0.58/10,000 patient-days/year (range 0.17-1.4). Candidemia episodes increased from 0.17/10,000 to 1.4/10,000 patient-days/year (p < 0.0001). Candida albicans and non-albicans Candida accounted for 15 (30%) and 35 (70%) cases, respectively. The overall mortality was 56% and was significantly associated with staying in the intensive care unit (odds ratio: 3.667, 95% confidence interval: 1.07-12.54, p = 0.034). Conclusion: This study showed that there was a significantly increased trend in the incidence of candidemia with high mortality during the study period. Copyright (C) 2010 S. Karger AG, Basel
dc.identifier.doi10.1159/000320305
dc.identifier.endpage467
dc.identifier.issn1011-7571
dc.identifier.issue6en_US
dc.identifier.pmid20881414
dc.identifier.scopus2-s2.0-77957688075
dc.identifier.scopusqualityQ2
dc.identifier.startpage463
dc.identifier.urihttps://doi.org/10.1159/000320305
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8666
dc.identifier.volume19
dc.identifier.wosWOS:000285419100008
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorErdem, İlknur
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofMedical Principles and Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNosocomial candidemia
dc.subjectIncidence
dc.subjectEtiology
dc.subjectMortality
dc.subjectBlood-Stream Infections
dc.subjectIntensive-Care
dc.subjectEpidemiology
dc.subjectUnit
dc.subjectPredictors
dc.subjectSurveillance
dc.subjectAlbicans
dc.subjectTrends
dc.subjectRates
dc.titleIncidence, Etiology and Risk Factors Associated with Mortality of Nosocomial Candidemia in a Tertiary Care Hospital in Istanbul, Turkey
dc.typeArticle

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