Comparison of the effect of erector spinae plane block for postoperative analgesia on neutrophil/lymphocyte ratio and platelet/lymphocyte ratio in patients operated for breast cancer

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dc.contributor.authorKaradil, Kübra Şahin
dc.contributor.authorGültekin, Ahmet
dc.contributor.authorŞahin, Ayhan
dc.contributor.authorGürdal, Sibel Özkan
dc.contributor.authorYıldırım, İlker
dc.contributor.authorArar, Cavidan
dc.date.accessioned2024-10-29T17:50:03Z
dc.date.available2024-10-29T17:50:03Z
dc.date.issued2024
dc.departmentTekirdağ Namık Kemal Üniversitesien_US
dc.description.abstractObjectives: It was seen that recurrence and metastasis after breast cancer surgery are related to the immune response of the host. Anesthetic agents modulate the surgical stress response or directly impair the functions of immune system cells. In our study, we aimed to compare the effects of nonsteroidal anti-inflammatory drugs and erector spinae plane block, which are among the methods we use for postoperative analgesia, on the neutrophil/lymphocyte ratio and platelet/lymphocyte ratio in patients undergoing breast cancer surgery. Methods: One hundred female patients aged 18-75 years, scheduled for unilateral breast cancer surgery, and who agreed to participate were included in our study. These cases were divided into two groups of the analgesia method: Those with erector spinae plane block (Group E) and those who were administered nonsteroidal anti-inflammatory drugs (Group N). According to the results, preoperative and postoperative neutrophil/lymphocyte ratio and platelet/lymphocyte ratio values were calculated and recorded. Results: Neutrophil/lymphocyte ratio and platelet/lymphocyte ratio were statistically higher in both groups in the postoperative period. No statistically significant difference was found when the preoperative and postoperative measurement changes of the laboratory parameters between the groups were compared. Postoperative VAS scores were statistically significantly lower in Group E. Conclusions: We concluded that when erector spinae plane block and nonsteroidal anti-inflammatory drug use were compared in managing postoperative analgesia in breast cancer surgery, their effects on the neutrophil/lymphocyte ratio and platelet/lymphocyte ratio were not superior to each other. However, the erector spinae plane block was superior for adequate pain control.en_US
dc.identifier.doi10.18621/eurj.1395544
dc.identifier.endpage397en_US
dc.identifier.issn2149-3189
dc.identifier.issue4en_US
dc.identifier.startpage388en_US
dc.identifier.trdizinid1245710en_US
dc.identifier.urihttps://doi.org/10.18621/eurj.1395544
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1245710
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12735
dc.identifier.volume10en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofThe European Research Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBreast canceren_US
dc.subjectstress responseen_US
dc.subjectneutrophil/lymphocyte ratio (NLR)en_US
dc.subjectplatelet/lymphocyte ratio (PLR)en_US
dc.subjecterector spinae plane block (ESPB)en_US
dc.titleComparison of the effect of erector spinae plane block for postoperative analgesia on neutrophil/lymphocyte ratio and platelet/lymphocyte ratio in patients operated for breast canceren_US
dc.typeArticleen_US

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