Factors Affecting Long-Term Survival Following Pulmonary Metastasectomy of Renal Cell Carcinoma

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dc.authorscopusid36712552600
dc.contributor.authorSarıçam, Murat
dc.date.accessioned2022-05-11T14:35:02Z
dc.date.available2022-05-11T14:35:02Z
dc.date.issued2020
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göğüs Cerrahisi Ana Bilim Dalı
dc.description.abstractPurpose: Role of pulmonary metastasectomy of renal cell carcinoma (RCC) is significant considering its contribution to survival rates. The aim of this study is to present the prognostic factors affecting the surgical outcomes and long-term survival. Materials and Methods: Forty-eight patients who had undergone pulmonary metastasectomy of RCC between 2000 and 2018 were analyzed in terms of gender, age, subtypes and pathological T stages of RCC, side and size of pulmonary metastases, disease-free interval (DFI) and type of lung resections in order to reveal the prognostic factors from the stand point of selecting suitable patients for lung metastasectomy. Results: Overall survival was 56.2 ± 21.7 months. Survival time was less than 3 years for 7 (14.6%), between 3 and 5 years for 11 (22.9%) and more than 5 years for 30 (62.5%) patients. Young age, female gender, unilateral pulmonary lesions, longer DFI, lung metastases limited in number and volume were statistically significant for better survival rates (P <.05) whereas subtypes and pathological stage of the primary tumor or the type of pulmonary metastasectomy did not act on the outcomes (P >.05). Conclusion: The most distinctive factor affecting the surgical outcomes is the complete resection of lung metas- tases rather than the extent of the surgery. This study clearly states that patients aged under 50 years with unilateral lung metastases counting less than 3 and measuring smaller than 4 cm3 , and also DFI lasting longer than 32 months benefit from pulmonary metastasectomy of RCC.
dc.identifier.doi10.22037/uj.v16i7.5927
dc.identifier.issn1735-1308
dc.identifier.issue5en_US
dc.identifier.pmid32869257
dc.identifier.scopus2-s2.0-85095673121
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.22037/uj.v16i7.5927
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8178
dc.identifier.volume17
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSarıçam, Murat
dc.language.isoen
dc.publisherUrology and Nephrology Research Centre
dc.relation.ispartofUrology Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectlung metastases
dc.subjectmetastasectomy
dc.subjectrenal cell carcinoma
dc.subjectsurgery
dc.subjectsurvival
dc.subjectadult
dc.subjectaged
dc.subjectfemale
dc.subjecthuman
dc.subjectkidney tumor
dc.subjectlung tumor
dc.subjectmale
dc.subjectmetastasis resection
dc.subjectmiddle aged
dc.subjectmortality
dc.subjectpathology
dc.subjectprognosis
dc.subjectrenal cell carcinoma
dc.subjectretrospective study
dc.subjectsurvival rate
dc.subjecttime factor
dc.subjectAdult
dc.subjectAged
dc.subjectCarcinoma, Renal Cell
dc.subjectFemale
dc.subjectHumans
dc.subjectKidney Neoplasms
dc.subjectLung Neoplasms
dc.subjectMale
dc.subjectMetastasectomy
dc.subjectMiddle Aged
dc.subjectPrognosis
dc.subjectRetrospective Studies
dc.subjectSurvival Rate
dc.subjectTime Factors
dc.titleFactors Affecting Long-Term Survival Following Pulmonary Metastasectomy of Renal Cell Carcinoma
dc.typeArticle

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