Determination of Antibiotic Resistance Pattern and Molecular Characterization of Corynebacterium pseudotuberculosis from Lymph Node Samples of Sheep and Goats in Ethiopia

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dc.contributor.authorYeshitila, Getaw
dc.contributor.authorGocmen, Huban
dc.contributor.authorYesilovali, Hazel Tamakan
dc.date.accessioned2024-10-29T17:43:31Z
dc.date.available2024-10-29T17:43:31Z
dc.date.issued2024
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractCorynebacterium pseudotuberculosis consists of non-motile and pleomorphic rods. The frequent rout of entry of C. pseudotuberculosis into the body of animal is in punctures and scratches of the skin. It results in the development of caseous abscesses in external and internal lymph nodes. Therefore, the following were the objectives of this research: to identify and isolate bacteriologically, to characterize molecularly C. pseudotuberculosis from the external nodes of lymph of sheep and goats, and to determine multiple drug resistance of C. pseudotuberculosis in sheep and goats in Halal Food Industries, Modjo, Ethiopia. A total of 450 animals (100 sheep and 350 goats) were examined during antemortem and postmortem inspections. Bacteriological isolation and identification of the collected lymph nodes were performed and then confirmed by PCR. Then, the antibiotic resistance profile was revealed. Seven (17.7%) of goat isolates from Oromia, 5 (12.5%) from Southern Nations, nationalities and peoples regional states and 4 (10%) sheep isolates from Oromia were evaluated as positive for C. pseudotuberculosis in molecular diagnosis. C. pseudotuberculosis was moderately susceptible to gentamicin (68.75%) and highly susceptible to penicillin G (100%), doxycycline (100%), and ciprofloxacin (100%) had been observed. In conclusion, risk associated factors and seroepidemiology of caseous lymphadenitis in sheep and goats should be investigated in Ethiopia. Copyright 2024 by the authors.
dc.description.sponsorshipMinistry of Education, MOE
dc.identifier.doi10.17582/journal.pjz/20230124090155
dc.identifier.endpage2261
dc.identifier.issn0030-9923
dc.identifier.issue5en_US
dc.identifier.scopus2-s2.0-85201197069
dc.identifier.scopusqualityQ4
dc.identifier.startpage2255
dc.identifier.urihttps://doi.org/10.17582/journal.pjz/20230124090155
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12450
dc.identifier.volume56
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherUniversity of Punjab (new Campus)
dc.relation.ispartofPakistan Journal of Zoology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntibiotic resistance
dc.subjectCaseous lymphadenitis
dc.subjectCorynebacterium pseudotuberculosis
dc.subjectLymph node
dc.subjectPCR
dc.titleDetermination of Antibiotic Resistance Pattern and Molecular Characterization of Corynebacterium pseudotuberculosis from Lymph Node Samples of Sheep and Goats in Ethiopia
dc.typeArticle

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