Prognostic Role of Tumor Percentage in Multiparametric MRI for Upgrade Prediction Before Radical Prostatectomy

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dc.authoridHereklioglu, Savas/0000-0002-5467-046X
dc.authoridSAHIN, MEHMET FATIH/0000-0002-0926-3005
dc.authoridecer, gokhan/0000-0002-2805-8664
dc.authoridGokalp, Fatih/0000-0003-3099-3317
dc.authoridArda, Ersan/0000-0002-5430-6561
dc.authoridYazici, Cenk Murat/0000-0001-6140-5181
dc.authoridAKGUL, BURAK/0000-0002-7931-1594
dc.contributor.authorArikan, Mehmet Guerkan
dc.contributor.authorEcer, Goekhan
dc.contributor.authorSahin, Mehmet Fatih
dc.contributor.authorHereklioglu, Savas
dc.contributor.authorGoekalp, Fatih
dc.contributor.authorArda, Ersan
dc.contributor.authorAkguel, Burak
dc.date.accessioned2024-10-29T17:59:40Z
dc.date.available2024-10-29T17:59:40Z
dc.date.issued2024
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractObjective: To determine the parameters that can predict upgrade with multiparametric magnetic resonance imaging (mpMRI) findings before radical prostatectomy Materials and Methods: The study included 69 patients who were diagnosed with prostate cancer (PCa) between January 2017-December 2020 and subsequently underwent RP. Patients were divided into two groups by comparing prostate biopsies and RP specimens as patients with upgrade (group 1) and patients without upgrade (group 2). Of the 69 patients, 26 were in group 1 and 43 in group 2. The images were evaluated by a single radiologist experienced in mpMRI using the Prostate Imaging Reporting and Data System v2.1 scoring system. Biopsy and RP pathology specimens were evaluated by an experienced neuropathologist. Results: The median prostate-specific antigen (PSA) levels were higher in patients with upgraded pathology [8.60 (5.90-14.00) ng/dL vs. 7.70 (5.20-10.00) ng/dL, respectively; p=0.040]. The prostate volume [31.88 (23.40-51.48) vs. 48.06 (23.40-87.35); p=0.009] and PSA density [3.72 (2.17-5.62) vs. 5.75 (3.35-9.6), respectively; p=0.007] were lower in patients with upgraded pathology. The tumor percentage on mpMRI was not different between the groups [3.70 (1.80-16.20 Conclusions: Although the percentage of tumors on multiparametric mpMRI is an inadequate pattern to predict upgrade in PCa patients, prospective studies
dc.identifier.doi10.4274/uob.galenos.2024.2023.7.1
dc.identifier.endpage41
dc.identifier.issn2147-2270
dc.identifier.issue1en_US
dc.identifier.startpage36
dc.identifier.trdizinid#BAŞV!
dc.identifier.urihttps://doi.org/10.4274/uob.galenos.2024.2023.7.1
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1240873
dc.identifier.urihttps://hdl.handle.net/20.500.11776/14805
dc.identifier.volume23
dc.identifier.wosWOS:001198126600003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofUroonkoloji Bulteni-Bulletin of Urooncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMultiparametric magnetic resonance imaging
dc.subjectprostate cancer
dc.subjectradical prostatectomy
dc.subjecttumor percentage
dc.subjectupgrade
dc.titlePrognostic Role of Tumor Percentage in Multiparametric MRI for Upgrade Prediction Before Radical Prostatectomy
dc.title.alternativePrognostic Role of Tumor Percentage in Multiparametric MRI for Upgrade Prediction Before Radical Prostatectomy
dc.typeArticle

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