Effect of CPAP on Hemocyte Profile C-reactive Protein and Fibrinogen Levels in People with Obstructive Sleep Apnea

Simple item page
dc.authoridYilmaz, Meltem/0000-0003-0314-4774
dc.contributor.authorYilmaz, Meltem
dc.contributor.authorMutlu, Levent Cem
dc.date.accessioned2024-10-29T17:59:37Z
dc.date.available2024-10-29T17:59:37Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractAim: Obstructive sleep apnea syndrome (OSAS) is a common sleep disorder characterized by repeated episodes of apnea and hypopnea during sleep. The repetitive hypoxemic and hypercapnic events can lead to increased proinflammatory cytokine production, endothelial dysfunction, oxidative stress, metabolic dysregulation, and insulin resistance in OSAS patients. In previous studies, some of the hemogram values increased in patients with OSAS and a decrease in these increased values was observed with continuous positive airway pressure (CPAP) treatment. CPAP is the most effective method for treating OSAS and alleviating the patients' symptoms. The aim of this study was to assess the effect of three-month CPAP therapy hemocyte profile in people with OSAS. Materials and Methods: Forty patients were included in the study. Data including clinical assessment, full previous polysomnography reports, and baseline and after CPAP therapy, complete blood profile (leukocytes, neutrophils, lymphocytes, hemoglobin, hematocrit, platelets, MPV, PDW, MCV, N/L, and P/L, CRP and fibrinogen) of the participants were collected from the electronic medical record. Results: All patients who completed the study were CPAP compliant (5.53 +/- 0.39 h/night). After three months of CPAP treatment, the mean levels leukocytes, lymphocytes, hemoglobin, hematocrit, MPV, MCV, N/L, and P/L, CRP and fibrinogen were significantly decreased compared to baseline values. Conclusion: Our study showed significant decrease in hemoglobin, hematocrit, leukocyte, lymphocyte, MPV, MCV, N/L, and P/L, CRP and fibrinogen after three-month CPAP therapy.
dc.identifier.doi10.4274/nkmj.galenos.2023.97658
dc.identifier.endpage53
dc.identifier.issn2587-0262
dc.identifier.issue1en_US
dc.identifier.startpage48
dc.identifier.trdizinid1175800
dc.identifier.urihttps://doi.org/10.4274/nkmj.galenos.2023.97658
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1175800
dc.identifier.urihttps://hdl.handle.net/20.500.11776/14790
dc.identifier.volume11
dc.identifier.wosWOS:001186705700013
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofNamik Kemal Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectObstructive sleep apnea syndrome
dc.subjectCPAP
dc.subjecthemocyte profile
dc.subjectCRP
dc.subjectfibrinogen
dc.titleEffect of CPAP on Hemocyte Profile C-reactive Protein and Fibrinogen Levels in People with Obstructive Sleep Apnea
dc.title.alternativeObstrüktif Uyku Apnesi Olan Kişilerde CPAP’ın Hemosit Profili, C-reaktif Protein ve Fibrinojen Düzeyleri Üzerine Etkisi
dc.typeArticle

Files

Collections

WoS İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu

We collect and process your personal information for the following purposes: Authentication, Preferences, Acknowledgement and Statistics.
To learn more, please read our privacy policy.

Customize