Implications of circulating irisin and Fabp4 levels in patients with polycystic ovary syndrome

Basit Öğe Kaydı
dc.authorid0000-0003-4973-2563
dc.authorid0000-0002-8182-2051
dc.authorscopusid6506061779
dc.authorscopusid56375903100
dc.authorscopusid41862830000
dc.authorscopusid24465134400
dc.authorscopusid41461297500
dc.authorscopusid36162768400
dc.authorscopusid43262210900
dc.authorwosidBULUT, BERK/AAD-4461-2022
dc.authorwosidbulut, berk/AAO-3323-2020
dc.contributor.authorAbalı, Remzi
dc.contributor.authorYüksel, İlkbal Temel
dc.contributor.authorYüksel, Mehmet Aytaç
dc.contributor.authorBulut, Berk
dc.contributor.authorİmamoğlu, Metehan
dc.contributor.authorEmirdar, Volkan
dc.contributor.authorÇelik, Cem
dc.contributor.authorGüzel, Savaş
dc.date.accessioned2022-05-11T14:35:53Z
dc.date.available2022-05-11T14:35:53Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractThe aim of the study was to evaluate the fatty acid-binding protein-4 (FABP4) and irisin concentrations in women with polycystic ovary syndrome (PCOS). Forty-nine women with PCOS, diagnosed according to Rotterdam criteria and 39 healthy women matched for body mass index (BMI) and age. Serum irisin and plasma FABP4 concentrations were measured in both groups. The association of irisin and FABP4 concentrations with metabolic parameters were also tested. Women with PCOS had significantly lower mean serum irisin concentrations than control subjects (158.5 +/- 123.3 versus 222.9 +/- 152.2ng/ml, p<0.05). Concentrations of FABP4 in PCOS and control groups were not significantly different (10.5 +/- 4.4 versus 10.9 +/- 4.2ng/ml, p>0.05). FABP4 concentrations were correlated with BMI, waist-hip ratio (WHR) and HOMA-IR (r=0.57, p=0.001; r=0.26, p=0.03; r=0.26, p=0.03, respectively). No associations between irisin and all the others parameters except serum levels of LH were found. Serum irisin concentrations of women with PCOS were lower compared to the controls. Moreover, there were no difference in plasma FABP4 concentrations between women with PCOS and controls.
dc.identifier.doi10.3109/01443615.2016.1174200
dc.identifier.endpage901
dc.identifier.issn0144-3615
dc.identifier.issn1364-6893
dc.identifier.issue7en_US
dc.identifier.pmid27184575
dc.identifier.scopus2-s2.0-84969194598
dc.identifier.scopusqualityQ3
dc.identifier.startpage897
dc.identifier.urihttps://doi.org/10.3109/01443615.2016.1174200
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8277
dc.identifier.volume36
dc.identifier.wosWOS:000390664700022
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAbalı, Remzi
dc.institutionauthorGüzel, Savaş
dc.institutionauthorÇelik, Cem
dc.language.isoen
dc.publisherTaylor & Francis Inc
dc.relation.ispartofJournal of Obstetrics and Gynaecology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectIrisin
dc.subjectFABP4
dc.subjectpolycystic ovary syndrome
dc.subjectAcid-Binding Protein
dc.subjectImpaired Glucose-Tolerance
dc.subjectType-2 Diabetes-Mellitus
dc.subjectInsulin-Resistance
dc.subjectMetabolic Syndrome
dc.subjectOxidative-Metabolism
dc.subjectSkeletal-Muscle
dc.subjectGranulosa-Cells
dc.subjectObesity
dc.subjectWomen
dc.titleImplications of circulating irisin and Fabp4 levels in patients with polycystic ovary syndrome
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
8277.pdf
Boyut:
435.6 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu