Relationship between fortilin levels and coronary ischemia in heart failure

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dc.contributor.authorGökçek, Sümeyra
dc.contributor.authorAydın, Cihan
dc.contributor.authorDemirkıran, Aykut
dc.contributor.authorAlpsoy, Şeref
dc.date.accessioned2024-10-29T17:50:03Z
dc.date.available2024-10-29T17:50:03Z
dc.date.issued2024
dc.departmentTekirdağ Namık Kemal Üniversitesien_US
dc.description.abstractObjective: Fortilin is a multifunctional protein that protects cells against apoptosis. We aimed to investigate the levels of fortilin in patients with heart failure. Methods: Patients with ejection fraction (EF) below 40% were divided into two groups according to coronary angiography results: those with ischemic heart failure (Group 1) and those with non-ischemic heart failure (Group 2). Patients with normal anatomy and EF over 50% were included in the control group (Group 3). Results: A total of 119 patients were prospectively included in the study. A total of 81 patients (41 patients with ischemic heart failure and 40 patients with non-ischemic heart failure) were included in the heart failure group. 38 patients with EF >50 and normal coronary anatomy were included in the control group. There was no significant difference in serum fortilin levels between the study groups (Group 1: 5.5±2.6 ng/mL, Group 2: 6.1±3.8 ng/mL, and Group 3: 5.6±3.6 ng/mL; P=0.693). Fortilin did not show a correlation with any other variables. Conclusion: In our study, there was no significant difference in fortilin levels between the groups, and no relationship was found between coronary ischemia and fortilin levels in heart failure.en_US
dc.identifier.doi10.18621/eurj.1447544
dc.identifier.endpage344en_US
dc.identifier.issn2149-3189
dc.identifier.issue4en_US
dc.identifier.startpage338en_US
dc.identifier.trdizinid1245704en_US
dc.identifier.urihttps://doi.org/10.18621/eurj.1447544
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1245704
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12736
dc.identifier.volume10en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofThe European Research Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHeart failureen_US
dc.subjectpro-BNPen_US
dc.subjectfortilinen_US
dc.subjectejection fractionen_US
dc.titleRelationship between fortilin levels and coronary ischemia in heart failureen_US
dc.typeArticleen_US

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