Prolactin receptor (PRLR) gene polymorphism in Chios, White Karaman and Awassi sheep breeds

Basit Öğe Kaydı
dc.authorid0000-0001-7460-4040
dc.authorid0000-0002-8577-7323
dc.authorwosidSeker, İbrahim/V-8805-2018
dc.authorwosidÜnal, Emel Özkan/ABA-3367-2020
dc.contributor.authorÖzmen, Özge
dc.contributor.authorŞeker, İbrahim
dc.contributor.authorErtuğrul, Okan
dc.contributor.authorÖzkan, Emel
dc.contributor.authorTekin, Nilgün
dc.date.accessioned2022-05-11T14:46:28Z
dc.date.available2022-05-11T14:46:28Z
dc.date.issued2011
dc.departmentFakülteler, Ziraat Fakültesi, Zootekni Bölümü
dc.description.abstractThe objective of the present study was to determine the polymorphism in the prolactine receptor (PRLR) gene in Chios, White Karaman and Awassi, which are native sheep breeds in Turkey. By means of PRLR gene sequence homology between sheep and humans, two primer pairs were designed for polymerase chain reaction (PCR) amplification within intron 1 and exon 10 of the PRLR gene in sheep. A total of 160 amplicons (99 for intron 1 and 61 for exon 10) were subjected to DNA sequence analysis. For intron 1, 6 different haplotypes were determined. For exon 10, 7 different haplotypes were obtained. Some variations determined for exon 10 (g.14A>T p.Q14L; g.160G>A p.D160N; g.166G>A p.E166K; g.167A>T p.E167V; g.176A>T p.H176L; g.206G>A p.S206N; g.208G>A p.G208R) led to changes in the amino acids, but no amino acid changes were determined in g.2A>T, g.81A>G, g.138A>G, g.186C>T, g..207T>C. It was noted in particular that White Karaman and Awassi were similar to each other in both PRLR exon 10 and intron 1 haplotypes, whereas the Chios breed had a different variation.
dc.description.sponsorshipTubitakTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); Council of Firat UniversityFirat University [1070894]
dc.description.sponsorshipThe sequence experiments were carried out at the Ankara University Biotechnology Institute Genomics Unit. The Project was supported by Tubitak and Scientific Research Projects Council of Firat University (Project code Tubitak 1070894; Fubap: 1502).
dc.identifier.doi10.5194/aab-54-381-2011
dc.identifier.endpage390
dc.identifier.issn0003-9438
dc.identifier.issue4en_US
dc.identifier.startpage381
dc.identifier.urihttps://doi.org/10.5194/aab-54-381-2011
dc.identifier.urihttps://hdl.handle.net/20.500.11776/10307
dc.identifier.volume54
dc.identifier.wosWOS:000297829200006
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.institutionauthorÖzkan, Emel
dc.language.isoen
dc.publisherArchiv Fur Tierzucht
dc.relation.ispartofArchiv Fur Tierzucht-Archives of Animal Breeding
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectTurkish sheep breeds
dc.subjectprolactin receptor gene
dc.subjectpolymorphism
dc.subject2 Forms
dc.subjectSignal-Transduction
dc.subjectStatistical Tests
dc.subjectDna Polymorphism
dc.subjectNull Mutation
dc.subjectLitter Size
dc.subjectExpression
dc.subjectMouse
dc.subjectChromosome-16
dc.subjectProlificacy
dc.titleProlactin receptor (PRLR) gene polymorphism in Chios, White Karaman and Awassi sheep breeds
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
10307.pdf
Boyut:
201.18 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Ziraat Fakültesi Koleksiyonu