Alterations of Ionized and Total Magnesium Levels in Pregnant Women with Gestational Diabetes Mellitus

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dc.authorscopusid56423637400
dc.authorscopusid23986422400
dc.authorscopusid55666290500
dc.authorscopusid6506061779
dc.authorscopusid24075279000
dc.authorscopusid54782578700
dc.contributor.authorGöker Taşdemir, Ufuk
dc.contributor.authorTaşdemir, Nicel
dc.contributor.authorKılıç, Sevtap
dc.contributor.authorAbalı, Remzi
dc.contributor.authorÇelik, Cem
dc.contributor.authorGülerman, Hacer Cavidan
dc.date.accessioned2022-05-11T14:35:52Z
dc.date.available2022-05-11T14:35:52Z
dc.date.issued2015
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı
dc.description.abstractBackground/Aims: The aim of this prospective study was to determine ionized and total magnesium (Mg) levels in pregnant subjects with and without gestational diabetes mellitus (GDM). Methods: Eighty-five women, 26-28 weeks pregnant, were recruited for routine oral glucose tolerance tests (OGTT); 45 had normal OGTT results and 40 were diagnosed with GDM. Electrolyte levels, including ionized and total Mg, were analyzed. Results: Gestational age and BMI were similar between the two groups (p = 0.800, p = 0.025). Multivitamin use was higher in the control group (p = 0.036). Fasting blood glucose was higher in the GDM group (p < 0.001). The median total Mg levels were 1.9 mg/dl (range 1.6-2.2) in the control group and 1.8 mg/dl (range 1.2-2.1) in the GDM group (p < 0.001). The median ionized Mg levels were 0.5 mmol/l (range 0.4-0.6) in the control group and 0.4 mmol/l (range 0.4-0.5) in the GDM group (p < 0.001). Conclusion: Our study revealed a relationship between low total and ionized Mg levels and GDM, as in type 2 diabetes mellitus (DM). The literature regarding type 2 DM and our findings suggest that Mg is the key ion in the pathophysiology of GDM. Low-dose Mg supplementation was not related to GDM; however, pharmacological doses in the various stages of pregnancy could be beneficial and should be investigated. (C) 2014 S. Karger AG, Basel
dc.identifier.doi10.1159/000365813
dc.identifier.endpage24
dc.identifier.issn0378-7346
dc.identifier.issn1423-002X
dc.identifier.issue1en_US
dc.identifier.pmid25413174
dc.identifier.scopus2-s2.0-84927961729
dc.identifier.scopusqualityQ2
dc.identifier.startpage19
dc.identifier.urihttps://doi.org/10.1159/000365813
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8271
dc.identifier.volume79
dc.identifier.wosWOS:000348046600003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTaşdemir, Nicel
dc.institutionauthorAbalı, Remzi
dc.institutionauthorÇelik, Cem
dc.language.isoen
dc.publisherKarger
dc.relation.ispartofGynecologic and Obstetric Investigation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMagnesium, ionized, total
dc.subjectPregnancy
dc.subjectGestational diabetes mellitus
dc.subjectSerum Magnesium
dc.subjectInsulin-Resistance
dc.subjectRisk
dc.subjectHypomagnesemia
dc.subjectDisorders
dc.subjectDisease
dc.titleAlterations of Ionized and Total Magnesium Levels in Pregnant Women with Gestational Diabetes Mellitus
dc.typeArticle

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