Red Cell Distribution Width and Acute Complications of Diabetes

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dc.authorid0000-0001-7213-9624
dc.authorid0000-0001-7213-9624
dc.authorscopusid56290776600
dc.authorscopusid56291092000
dc.authorscopusid57205651577
dc.authorscopusid23968920100
dc.authorscopusid15727384300
dc.authorscopusid8525219800
dc.authorwosiderman, hande/AAP-6507-2021
dc.authorwosidBOYUK, BANU/ABA-7026-2021
dc.authorwosiderman, hande/AAZ-7697-2021
dc.contributor.authorAtalay, Hande
dc.contributor.authorBoyuk, B.
dc.contributor.authorAteş, Murat
dc.contributor.authorGüzel, Savaş
dc.contributor.authorÇelebi, A.
dc.contributor.authorEkizoğlu, İsmail
dc.date.accessioned2022-05-11T14:42:06Z
dc.date.available2022-05-11T14:42:06Z
dc.date.issued2018
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractContext. Red cell distribution width (RDW) has been associated with type 2 diabetes (T2DM), however data in relation to diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar non-ketotic acidosis (HONK) remains unclear. Objective. The aim of this study was to evaluate the association between RDW, MCV, and RDW/MVC values and acute complications in T2DM. Patients and Methods. RDW was measured in 90 T2DM patients (30 DKA, 30 HONK and 30 T2DM without acute complications). Clinical variables were analyzed by One -Way ANOVA, Kruskal-Wallis and Pearson analysis with SPSS software. Diagnostic screening tests and ROC curve analysis determined the cut-off point of MCV,RDW and RDW/MCV values. Results. DKA patients had higher levels of plasma glucose (524.20 +/- 201.43mg/dL, p<0.001), HbA1c (10.73 +/- 2.29%, p<0.001), osmotic pressure (310.32 mosm/L, p<0.001), RDW (14.61 +/- 1.75g/L, p<0.01), and the RDW/MCV ratio (0.17 +/- 0.04%, p<0.01), compared to HONK patients. RDW/MCV cut-off value was 0.15 with 90% sensitivity 50% specifity these values for only MCV were 76.67%-70%, for only RDW were 76.67%-63.33% respectively. The area under curve values for the ability to reflect DKA for RDW and the RDW/MCV ratio were 0.708 and 0.766, respectively (p<0.001). Conclusions. RDW and RDW/MCV ratio were found associated with DKA and valuable in predicting DKA. However these parameters were not valuable in predicting HONK.
dc.identifier.doi10.4183/aeb.2018.514
dc.identifier.endpage519
dc.identifier.issn1841-0987
dc.identifier.issn1843-066X
dc.identifier.issue4en_US
dc.identifier.pmid31149305
dc.identifier.scopus2-s2.0-85060905824
dc.identifier.scopusqualityQ4
dc.identifier.startpage514
dc.identifier.urihttps://doi.org/10.4183/aeb.2018.514
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9222
dc.identifier.volume14
dc.identifier.wosWOS:000465157500012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGüzel, Savaş
dc.language.isoen
dc.publisherEditura Acad Romane
dc.relation.ispartofActa Endocrinologica-Bucharest
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectrdw
dc.subjectdiabetic ketoacidosis
dc.subjectHONK
dc.subjectC-Reactive Protein
dc.subjectRisk
dc.subjectInflammation
dc.subjectHemoglobin
dc.subjectAssociation
dc.subjectParameters
dc.subjectMellitus
dc.subjectMarkers
dc.subjectAdults
dc.subjectVolume
dc.titleRed Cell Distribution Width and Acute Complications of Diabetes
dc.typeArticle

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