Synaptic noise facilitates the emergence of self-organized criticality in the Caenorhabditis elegans neuronal network

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dc.authorscopusid6603952578
dc.contributor.authorÇiftçi, Koray
dc.date.accessioned2022-05-11T14:16:06Z
dc.date.available2022-05-11T14:16:06Z
dc.date.issued2018
dc.departmentFakülteler, Çorlu Mühendislik Fakültesi, Biyomedikal Mühendisliği Bölümü
dc.description.abstractAvalanches with power-law distributed size parameters have been observed in neuronal networks. This observation might be a manifestation of self-organized criticality (SOC). Yet, the physiological mechanisms of this behaviour are currently unknown. Describing synaptic noise as transmission failures mainly originating from the probabilistic nature of neurotransmitter release, this study investigates the potential of this noise as a mechanism for driving the functional architecture of the neuronal networks towards SOC. To this end, a simple finite state neuron model, with activity dependent and synapse specific failure probabilities, was built based on the known anatomical connectivity data of the nematode Ceanorhabditis elegans. Beginning from random values, it was observed that synaptic noise levels picked out a set of synapses and consequently an active subnetwork that generates power-law distributed neuronal avalanches. The findings of this study bring up the possibility that synaptic failures might be a component of physiological processes underlying SOC in neuronal networks. © 2018, © 2018 Taylor & Francis.
dc.identifier.doi10.1080/0954898X.2018.1535721
dc.identifier.endpage19
dc.identifier.issn0954-898X
dc.identifier.issue45383en_US
dc.identifier.pmid30340443
dc.identifier.scopus2-s2.0-85055562449
dc.identifier.scopusqualityQ4
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.1080/0954898X.2018.1535721
dc.identifier.urihttps://hdl.handle.net/20.500.11776/6177
dc.identifier.volume29
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÇiftçi, Koray
dc.language.isoen
dc.publisherTaylor and Francis Ltd
dc.relation.ispartofNetwork: Computation in Neural Systems
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCaenorhabditis elegans
dc.subjectcriticality
dc.subjectnetwork
dc.subjectneuron
dc.subjectnoise
dc.subjectSelf organization
dc.subjectsynapse
dc.subjectanatomy and histology
dc.subjectanimal
dc.subjectbiological model
dc.subjectCaenorhabditis elegans
dc.subjectcytology
dc.subjectnerve cell
dc.subjectnerve cell network
dc.subjectnervous system
dc.subjectnonlinear system
dc.subjectphysiology
dc.subjectprobability
dc.subjectsynapse
dc.subjectAnimals
dc.subjectCaenorhabditis elegans
dc.subjectModels, Neurological
dc.subjectNerve Net
dc.subjectNervous System
dc.subjectNeurons
dc.subjectNonlinear Dynamics
dc.subjectProbability
dc.subjectSynapses
dc.titleSynaptic noise facilitates the emergence of self-organized criticality in the Caenorhabditis elegans neuronal network
dc.typeArticle

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