Ankilozan Spondiliti Olan Hastalarda Depresyonun, Hastalık Aktivitesi ve Yaşam Kalite Ölçekleri Üzerine Etkileri
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Dosyalar
Tarih
2018
Yazarlar
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç Bu çalışmanın amacı, AS hastalarında depresyonun sıklığını ve depresyonun hastalık aktivite ve yaşam kalite ölçekleri üzerine olan etkilerinideğerlendirmektir.Sakarya Tıp Dergisi, 2018, 8(2):371-378 )Gereç veYöntemÇalışmamıza modifi ye New York Kriterlerine göre AS tanısı almış 144 hasta dahil edildi. Depresyon düzeyi değerlendirilmesi için BeckDepresyon Ölçeği (BDÖ), anksiyete değerlendirmesi için ise Beck Anksiyete Ölçeği (BAÖ) formları kullanıldı. AS hastalarında hastalıkaktivitesi Bath AS Hastalık Aktivite İndeksi (BASDAİ) ile, spinal mobilite Bath AS metroloji indeksi (BASMİ) ile ve fonksiyonel durum ise BathAS fonksiyonel indeksi (BASFİ) ile değerlendirildi. Yaşam kalitesini değerlendirmek için bir çok farklı indeks kullanılarak depresyon ile buparametreler arasındaki ilişkiler analiz edildi.Bulgular Çalışmaya dahil edilen 144 AS hastasının %71.5’u erkekti ve ortalama yaşları ise 39.07 (10.8) olarak saptandı. Hastaların %27.5’indeBDÖ’ye göre depresyon ve %33.6’sında BAÖ’e göre orta ve yüksek düzeyde anksiyete tespit edildi. BDÖ’ye göre depresyonda olanhastaların BASDAİ ve BASFİ ile ölçülen hastalık aktivitesi yüksek olarak bulundu (sırasıyla, p=0.008, p=0.002). Depresyonu olan hastalardatüm yaşam kalite ölçeklerinde olumsuz yönde bir etkilenme vardı. Depresyonu olan hastalarda anksiyete sıklığı da yüksekti. BASDAİ ? 4 olanhastalarda depresyon sıklığının 1.55 kat (%95 güvenlik aralığında 1.043-2.31, p<0.05) arttığı gözlemlendi.Sonuç AS hastalarında psikiyatrik durum değerlendirmesi klinik değerlendirmenin bir parçası olarak düşünülebilir. Depresyonun da katkıdabulunduğu yasam kalitesindeki bozulmanın düzeltilmesini hedefl eyen tedavi yöntemleri, hastanın AS tedavisine uyumuna da katkısağlayabilir.
Purpose The aim of this study is to evaluate the frequency of depression in patients with AS and the effects of depression on disease activity and the quality of life indices. ( Sakarya Med J, 2018, 8(2):371-378 ). Materials and Methods One hundred forty-four patients diagnosed as AS according to modifi ed New York criteria were included to the study. Beck Depression Index (BDI) was used to assess depression level and Beck Anxiety Index (BAI) was used to evaluate anxiety. The disease activity was assessed by the Bath AS Disease Activity Index (BASDAI), spinal mobility by the Bath AS metrology index (BASMI) and the functional status by the Bath AS functional index (BASFI). A number of different indices were used to assess quality of life and the relationships between depression and these parameters were analyzed. Results Of the 144 AS patients included to the study, 71.5% were male and the mean age was 39.07 (10.8). Depression according to BDI was detected in 27.5% of patients and middle and high-level anxiety according to BAI were in 33.6% of patients. Patients with depression according to BDI had signifi cantly higher disease activity measured by BASDAI and BASFI (p = 0.008, p = 0.002, respectively). Patients with depression had a negative impact on all quality of life indices. Patients with depression had also higher frequency of anxiety. The frequency of depression increased 1.55 fold (95% confi dence interval 1.043-2.31, p <0.05) in patients with BASDAI ? 4. Conclusion The evaluation of psychiatric status may be considered as a component of clinical evaluation in patients with AS. The therapeutic methods that aim to improve the deterioration of quality of life may also contribute to patients’ compliance to AS treatment.
Purpose The aim of this study is to evaluate the frequency of depression in patients with AS and the effects of depression on disease activity and the quality of life indices. ( Sakarya Med J, 2018, 8(2):371-378 ). Materials and Methods One hundred forty-four patients diagnosed as AS according to modifi ed New York criteria were included to the study. Beck Depression Index (BDI) was used to assess depression level and Beck Anxiety Index (BAI) was used to evaluate anxiety. The disease activity was assessed by the Bath AS Disease Activity Index (BASDAI), spinal mobility by the Bath AS metrology index (BASMI) and the functional status by the Bath AS functional index (BASFI). A number of different indices were used to assess quality of life and the relationships between depression and these parameters were analyzed. Results Of the 144 AS patients included to the study, 71.5% were male and the mean age was 39.07 (10.8). Depression according to BDI was detected in 27.5% of patients and middle and high-level anxiety according to BAI were in 33.6% of patients. Patients with depression according to BDI had signifi cantly higher disease activity measured by BASDAI and BASFI (p = 0.008, p = 0.002, respectively). Patients with depression had a negative impact on all quality of life indices. Patients with depression had also higher frequency of anxiety. The frequency of depression increased 1.55 fold (95% confi dence interval 1.043-2.31, p <0.05) in patients with BASDAI ? 4. Conclusion The evaluation of psychiatric status may be considered as a component of clinical evaluation in patients with AS. The therapeutic methods that aim to improve the deterioration of quality of life may also contribute to patients’ compliance to AS treatment.
Açıklama
Anahtar Kelimeler
Hematoloji, Genel ve Dahili Tıp, Psikiyatri
Kaynak
Sakarya Tıp Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
8
Sayı
2
