Ten-Year Outcomes Following Revascularization Strategies for Non-ST-Segment Elevation Myocardial Infarction and Multivessel Disease

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dc.contributor.authorDemirkiran, Aykut
dc.contributor.authorAydin, Cihan
dc.contributor.authorAkyuz, Aydin
dc.contributor.authorAlpsoy, Seref
dc.date.accessioned2025-04-06T12:23:39Z
dc.date.available2025-04-06T12:23:39Z
dc.date.issued2025
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractObjective: There remain conflicting recommendations regarding revascularization strategies for patients with non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel disease (MVD). This study aimed to compare the long-term outcomes of different revascularization strategies. Method: Patients with similar characteristics were categorized into three groups: immediate complete revascularization (ICR), staged complete revascularization (SCR), and non-complete revascularization (NCR). The SCR group was further divided based on the time interval between the index and staged procedures: SCR <= 24 hours and SCR > 24 hours. Cardiac composite outcomes included the total number of cardiac deaths and recurrent myocardial infarction during the follow-up period. Results: Out of 14,511 screened patients, 316 were included in the analysis. The results showed a significant difference in risk between SCR and ICR (hazard ratio [HR] (95% confidence interval [CI]): 0.27 (0.15-0.47); P = 0.001). There was no significant difference between NCR and SCR (HR (95% CI): 1.06 (0.61-1.84); P = 0.832). The SCR group was divided into two groups based on the time interval from the first to the second procedure (time interval [TI] <= 24 hours in the SCR1 group, and TI > 24 hours in the SCR2 group). The frequency of cardiac composite outcomes was lower in SCR1 compared to SCR2 (16.7% vs. 47.1%; P = 0.038). Conclusion: Our findings support the use of ICR and SCR completed within 24 hours due to their favorable long-term outcomes in patients with MVD and NSTEMI.
dc.identifier.doi10.5543/tkda.2024.59839
dc.identifier.endpage99
dc.identifier.issn1016-5169
dc.identifier.issn1308-4488
dc.identifier.issue2
dc.identifier.pmid40035253
dc.identifier.scopus2-s2.0-86000163022
dc.identifier.scopusqualityQ3
dc.identifier.startpage93
dc.identifier.urihttps://doi.org/10.5543/tkda.2024.59839
dc.identifier.urihttps://hdl.handle.net/20.500.11776/17094
dc.identifier.volume53
dc.identifier.wosWOS:001451191900003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKare Publ
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250406
dc.subjectComplete revascularization
dc.subjectinfarct-related artery
dc.subjectmultivessel disease
dc.subjectrevascularization strategies
dc.subjectnon-ST-segment elevation myocardial infarction
dc.titleTen-Year Outcomes Following Revascularization Strategies for Non-ST-Segment Elevation Myocardial Infarction and Multivessel Disease
dc.typeArticle

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