Evaluation of the efficacy of topical rifamycin application on postoperative complications after lower impacted wisdom teeth surgery

dc.authoridFeslihan, Erkan/0000-0003-4082-3039
dc.contributor.authorCigerim, Levent
dc.contributor.authorOrhan, Zeynep Dilan
dc.contributor.authorKaplan, Volkan
dc.contributor.authorCigerim, Saadet Cinarsoy
dc.contributor.authorFeslihan, Erkan
dc.date.accessioned2024-10-29T17:58:27Z
dc.date.available2024-10-29T17:58:27Z
dc.date.issued2024
dc.departmentTekirdağ Namık Kemal Üniversitesien_US
dc.description.abstractPurpose: This study aimed to evaluate the efficacy of a single-dose topical rifamycin application on postoperative complications after impacted lower third molar surgery. Materials and methods: This prospective, controlled clinical study consisted of individuals with bilaterally impacted lower third molars that would be extracted for orthodontic reasons. The extraction sockets were irrigated with 3 ml/250 mg of rifamycin solution in Group 1, while in Group 2 (control group) the extraction sockets were irrigated with 20 ml of physiological saline. Pain intensity was measured daily for 7 days by using visual analog scale. Trismus and edema were evaluated preoperatively and on the postoperative days 2 and 7 by calculating the proportional changes in maximum mouth opening and mean distance between reference points of the face, respectively. Paired samples t-test, Wilcoxon signed rank test and Chi-square test were used to analyze the study variables. Results: 35 patients (19 female, 16 male) were included in the study. The mean age of all participants was 22.19 4.98. Alveolitis was observed in 8 patients, (6 in the control group, 2 in the rifamycin group). There was no statistically significant difference between groups in terms of trismus and swelling measurements on the 2nd and 7th postoperative days (p>0.05). VAS scores were significantly low in rifamycin group on postoperative days 1 and 4 (p<0.05). Conclusion: Within the limits of the present study, topical rifamycin application reduced the incidence of alveolitis, prevented infection, and provided analgesic effect after surgical removal of impacted third molars. (c) 2023 Elsevier Masson SAS. All rights reserved.en_US
dc.description.sponsorshipThe authors thank Emire Bor (Expert Statistician, EMPIAR Statisti-cal Consulting, I_stanbul, Turkey) for her assistance in the statistical evaluation of the data and review of methodology.en_US
dc.identifier.doi10.1016/j.jormas.2023.101501
dc.identifier.issn2468-8509
dc.identifier.issn2468-7855
dc.identifier.issue4en_US
dc.identifier.pmid37178873en_US
dc.identifier.scopus2-s2.0-85174458986en_US
dc.identifier.urihttps://doi.org/10.1016/j.jormas.2023.101501
dc.identifier.urihttps://hdl.handle.net/20.500.11776/14330
dc.identifier.volume125en_US
dc.identifier.wosWOS:001308729900044en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofJournal of Stomatology Oral and Maxillofacial Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectRifamycinen_US
dc.subjectImpacted lower third molaren_US
dc.subjectOral surgeryen_US
dc.subjectPainen_US
dc.subjectTrismusen_US
dc.subjectEdemaen_US
dc.titleEvaluation of the efficacy of topical rifamycin application on postoperative complications after lower impacted wisdom teeth surgeryen_US
dc.typeArticleen_US

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