Understanding potential associations between anatomic and other factors in OSA severity

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dc.authorid0000-0002-2891-3501
dc.authorscopusid55770607000
dc.authorscopusid15055538600
dc.authorscopusid57208880300
dc.authorscopusid26648338400
dc.authorscopusid54892706700
dc.contributor.authorErsözlü, Tolga
dc.contributor.authorDeniz, Mahmut
dc.contributor.authorFazlıoğlu, Nevin
dc.contributor.authorGültekin, Erdoğan
dc.contributor.authorAltıntaş, Nejat
dc.date.accessioned2022-05-11T14:12:38Z
dc.date.available2022-05-11T14:12:38Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun ve Boğaz Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalı
dc.description.abstractPurpose The aim of this prospective study was to investigate associations between nasal/oropharyngeal structures and a range of factors including age, gender, daytime sleepiness, and body mass index (BMI). Methods Patients with OSA were prospectively selected as research participants in rhinomanometric analysis as well as for otolaryngological evaluation. Participants were grouped as follows according to their apnea/hypopnea index (AHI) scores: no OSA (AHI < 5), mild OSA (5 <= AHI <= 15), moderate OSA (15 <= AHI < 30), and severe OSA (AHI >= 30). One-way analysis of variance (ANOVA), Kruskal-Wallis H, and Mann-Whitney U tests were performed to assess OSA severity in terms of the relationships between nasal resistance (NR) and anthropometric indices (body mass index (BMI), Friedman tongue position (FTP)), age, and gender. Results The study cohort of 177 men and 81 women ranged in age between 21 and 76 years, with BMI ranging from 23 to 45. In total, 37 patients were simple snorers (AHI < 5), and 221 patients were diagnosed with OSA. There was no significant difference among the AHI groups in terms of nasal volume (Vol05) (p = 0.952), mean flow (p = 0.778), and mean NR total (p = 0.723). A statistically significant difference was found between the AHI groups in terms of mean BMI and median FTP scores (p < 0.001). Conclusion This study provides evidence that that the oropharyngeal region (oropharynx, tongue, and vallecula) is a more important determinant of OSA severity than the nasal region.
dc.identifier.doi10.1007/s11325-021-02539-1
dc.identifier.issn1520-9512
dc.identifier.issn1522-1709
dc.identifier.pmid34841491
dc.identifier.scopus2-s2.0-85120089626
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1007/s11325-021-02539-1
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5625
dc.identifier.wosWOS:000723080800001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorErsözlü, Tolga
dc.institutionauthorDeniz, Mahmut
dc.institutionauthorFazlıoğlu, Nevin
dc.institutionauthorGültekin, Erdoğan
dc.institutionauthorAltıntaş, Nejat
dc.language.isoen
dc.publisherSpringer Heidelberg
dc.relation.ispartofSleep and Breathing
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectObstructive sleep apnea
dc.subjectTotal nasal resistance
dc.subjectFriedman tongue position
dc.subjectRhinomanometry
dc.subjectApnea index
dc.subjectBody mass index
dc.subjectObstructive Sleep-Apnea
dc.subjectMallampati Score
dc.subjectNasal Resistance
dc.subjectFat Distribution
dc.titleUnderstanding potential associations between anatomic and other factors in OSA severity
dc.typeArticle

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