The importance of GRACE risk score in the development of high-grade atrioventricular conduction blocks after non-st-segment elevation myocardial infarction

dc.authoridAydin, Cihan/0000-0002-1401-5727
dc.contributor.authorUyan, U.
dc.contributor.authorAydin, C.
dc.contributor.authorGul, I.
dc.date.accessioned2024-10-29T18:00:20Z
dc.date.available2024-10-29T18:00:20Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractOBJECTIVE: The development of high-grade atrioventricular block (HG-AVB) after acute coronary syndrome (ACS) increases morbidity and mortality rates. A significant por-tion of HG-AVBs resolve spontaneously after re-vascularization. We aimed to evaluate the pow-er of the GRACE scoring system in predicting the development of HG-AVB and its importance in determining the need for cardiac pacemakers. PATIENTS AND METHODS: Patients who ap-plied to our center between July 2020 and Feb-ruary 2023 were included in the study. 600 pa-tients [340 (56.6%) male, mean age 65.4 +/- 13.6] without ST-segment elevation (NSTEMI) and who underwent revascularization were evalu-ated within the scope of the study. The heart rhythms of the patients were evaluated from the electrocardiograms (ECG) at admission. Pa-tients with HG-AVB and other patients were di-vided into two groups. The heart rhythms of these patients were evaluated during their hos-pitalization. Then, HG-AVB patients were also divided into two groups (with and without PPM need). Demographic, laboratory, angiographic, and echocardiographic characteristics of these patients were evaluated. RESULTS: Morbidity and mortality were high-er in the HG-AVB group. These patients had lon-ger intensive care and hospital stays. The mean age, creatinine value, GRACE score (GS), to-tal cholesterol (TC), and RCA lesion rates were higher in the HG-AVB group; hemoglobin level was found to be lower. As a result of regression analysis, RCA lesion, hemoglobin value, GRACE score, creatinine, and TC levels were predic-tors of HG-AVB development. In determining the need for PPM, these variables were found to be effective. ROC analysis was performed for GS, which predicted the development of HG-AVB, and the cut-off value was found to be 185.5. CONCLUSIONS: The development of HG-AVB after NSTEMI is an important health problem. By detecting these patients and those who may need PPM beforehand, various complications can be prevented, and the length of stay in the hospital can be shortened. Calculation of GS is an important parameter that can be used to pre-dict the development and course of HG-AVB.
dc.identifier.endpage9780
dc.identifier.issn1128-3602
dc.identifier.issue20en_US
dc.identifier.pmid37916341
dc.identifier.startpage9773
dc.identifier.urihttps://hdl.handle.net/20.500.11776/14982
dc.identifier.volume27
dc.identifier.wosWOS:001113903000040
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectNon-ST segment elevation myocardial infarction
dc.subjectHigh-grade atrioventricular conduction block
dc.subjectGRACE risk score
dc.subjectPermanent pacemaker
dc.titleThe importance of GRACE risk score in the development of high-grade atrioventricular conduction blocks after non-st-segment elevation myocardial infarction
dc.typeArticle

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