Changes in serum adenosine deaminase and isoenzyme levels in addition to routine liver biochemical parameters in sheep with chronic fascioliasis

Basit Öğe Kaydı
dc.authorid0000-0001-5805-0340
dc.authorwosidAltug, Nuri/E-3427-2018
dc.contributor.authorAltuğ, Nuri
dc.contributor.authorBaşbuğan, Yildiray
dc.contributor.authorYüksek, Nazmi
dc.date.accessioned2022-05-11T14:05:14Z
dc.date.available2022-05-11T14:05:14Z
dc.date.issued2022
dc.departmentFakülteler, Veteriner Fakültesi, Klinik Bilimler Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractThis study assessed changes in the levels of adenosine deaminase (ADA) and its isoenzymes in addition to routine liver biochemical parameters in sheep with fascioliasis. The study was conducted on 35 Akkaraman sheep. Of these, 25 sheep were diagnosed with fascioliasis based on anamnesis and clinical signs, and had endoparasites based on parasitological examinations (Fasciola-infected group). The remaining 10 sheep that were sampled from a single healthy herd (same flock) different from the infected group did not have any clinical signs or endoparasites (control group). Total protein (TP), albumin (ALB), and globulin (GLB) levels gradually increased on days after treatment compared to the values measured before treatment; the increases were statistically significant on all days for TP levels but only on day 14 after treatment for GLB levels (P < 0.05). Although, the ALB levels did not increase significantly on days after treatment, the ALB level and ALB/GLB ratio on days 7 and 14 after treatment were still lower than the values of day 21 after treatment and control group (P < 0.05). Total bilirubin (T-Bil) and direct bilirubin (D-Bil) levels on days 14 and 21 were significantly lower than that of day 0 (before treatment) and day 7 after treatment (P < 0.05). These results indicated that the increase in adenosine deaminase (ADA) and ADA1 levels may be due to possible concomitant infection of Fasciola larvae (in the parenchyma) and adults (in the bile duct).
dc.description.sponsorshipScientific Research Projects Commission of Van Yuzuncu Yil University [TAP-2019-8333]
dc.description.sponsorshipThis study was supported by the Scientific Research Projects Commission of Van Yuzuncu Yil University (Project No: TAP-2019-8333).
dc.identifier.doi10.1590/0103-8478cr20210152
dc.identifier.issn0103-8478
dc.identifier.issn1678-4596
dc.identifier.issue4en_US
dc.identifier.urihttps://doi.org/10.1590/0103-8478cr20210152
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4931
dc.identifier.volume52
dc.identifier.wosWOS:000706102200001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAltuğ, Nuri
dc.language.isoen
dc.publisherUniv Federal Santa Maria
dc.relation.ispartofCiencia Rural
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectadenosine deaminase
dc.subjectbiochemistry
dc.subjectdiagnosis
dc.subjectFasciola spp.
dc.subjectsheep
dc.subjectSubclinical Fascioliasis
dc.subjectOvine Fascioliasis
dc.subjectHepatica
dc.subjectGigantica
dc.subjectInfection
dc.subjectResponses
dc.subjectDiseases
dc.subjectTissues
dc.subjectUpdate
dc.subjectCattle
dc.titleChanges in serum adenosine deaminase and isoenzyme levels in addition to routine liver biochemical parameters in sheep with chronic fascioliasis
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
4931.pdf
Boyut:
575.76 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Veteriner Fakültesi Koleksiyonu