Quantitative evaluation of computed tomography findings in patients with pulmonary embolism: the link between D-Dimer level and thrombus volume

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dc.authorscopusid36009433000
dc.authorscopusid8531050000
dc.contributor.authorSasani, Hadi
dc.contributor.authorMutlu, Levent Cem
dc.date.accessioned2022-05-11T14:02:49Z
dc.date.available2022-05-11T14:02:49Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyoloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Göğüs Hastalıkları Ana Bilim Dalı
dc.description.abstractOBJECTIVE: To investigate the correlation of D-dimer levels and computed tomography properties of pulmonary embolism. METHODS: A total of 58 treated patients with diagnosis of properties of pulmonary embolism were retrospectively studied. All patients underwent a D-dimer blood test. In computed tomography images, septal angle, interventricular septal thickness, and the diameters of all cardiac chambers and pulmonary arteries were measured. The thrombus volume (load) and density at all pulmonary arteries (main, right, left pulmonary arteries, and segmental arteries) were calculated. RESULTS: A significant correlation was found between D-dimer and total thrombus volume (p=0.009, r=0.342). Total thrombus volume and total thrombus density were calculated with mean value of 23.40±60.63 ml and 66.16±38.48 hounsfield unit (HU), respectively. Right ventricle/left ventricle ratio showed positive correlation with the D-dimer level (p=0.02). CONCLUSION: Increased D-dimer levels with RV/LV ratio and their correlation with total thrombus volume suggest that it may be a prognostic factor. © 2021 Associacao Medica Brasileira. All rights reserved.
dc.identifier.doi10.1590/1806-9282.67.02.20200539
dc.identifier.endpage223
dc.identifier.issn0104-4230
dc.identifier.issue2en_US
dc.identifier.pmid34406245
dc.identifier.scopus2-s2.0-85113319505
dc.identifier.scopusqualityQ3
dc.identifier.startpage218
dc.identifier.urihttps://doi.org/10.1590/1806-9282.67.02.20200539
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4502
dc.identifier.volume67
dc.identifier.wosWOS:000686262400013
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSasani, Hadi
dc.institutionauthorMutlu, Levent Cem
dc.language.isoen
dc.publisherAssociacao Medica Brasileira
dc.relation.ispartofRevista da Associacao Medica Brasileira
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectD-dimer
dc.subjectPulmonary embolism
dc.subjectQuantitative analysis
dc.subjectThrombosis
dc.subjectX-Ray computed tomography
dc.subjectD dimer
dc.subjectfibrin degradation product
dc.subjectfibrin fragment D
dc.subjectadult
dc.subjectaged
dc.subjectartery diameter
dc.subjectArticle
dc.subjectblood vessel parameters
dc.subjectcomputed tomography pulmonary angiography
dc.subjectcomputer assisted tomography
dc.subjectcontrolled study
dc.subjectdisease course
dc.subjectfemale
dc.subjecthuman
dc.subjectimage analysis
dc.subjectinformation processing
dc.subjectinterventricular septum
dc.subjectlaboratory test
dc.subjectleft pulmonary artery
dc.subjectlung embolism
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmiddle aged
dc.subjectoccult blood test
dc.subjectpopulation structure
dc.subjectpulmonary artery
dc.subjectquantitative analysis
dc.subjectretrospective study
dc.subjectright pulmonary artery
dc.subjectthrombus
dc.subjectthrombus density
dc.subjectthrombus volume
dc.subjectdiagnostic imaging
dc.subjectlung embolism
dc.subjectthrombosis
dc.subjectx-ray computed tomography
dc.subjectFibrin Fibrinogen Degradation Products
dc.subjectHumans
dc.subjectPulmonary Embolism
dc.subjectRetrospective Studies
dc.subjectThrombosis
dc.subjectTomography, X-Ray Computed
dc.titleQuantitative evaluation of computed tomography findings in patients with pulmonary embolism: the link between D-Dimer level and thrombus volume
dc.typeArticle

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