B-type natriuretic peptide levels in patients with COPD and normal right ventricular function

Basit Öğe Kaydı
dc.authorid0000-0002-5992-545X
dc.authorscopusid16315694300
dc.authorscopusid16315443300
dc.authorscopusid24366172600
dc.authorscopusid10144122400
dc.authorscopusid23095215100
dc.authorscopusid6602723377
dc.authorscopusid6603675780
dc.authorwosidOnes, Tunc/A-8166-2019
dc.contributor.authorGemici, Gökmen
dc.contributor.authorErdim, Refik
dc.contributor.authorÇeliker, Aydın
dc.contributor.authorTokay, Sena
dc.contributor.authorÖnes, Tunc
dc.contributor.authorİnanır, Sabahat
dc.contributor.authorOktay, Ahmet
dc.date.accessioned2022-05-11T14:40:05Z
dc.date.available2022-05-11T14:40:05Z
dc.date.issued2008
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractIntroduction: Evidence suggests that elevated plasma levels of B-type natriuretic peptide (BNP) are found in patients with chronic obstructive pulmonary disease (COPD) and right ventricular dysfunction. We examined the effects of exercise on plasma BNP levels in patients with COPD who have normal right ventricular function. Methods: Seventeen patients with a diagnosis of COPD and normal right ventricular function demonstrated by radionuclide ventriculography, and 17 age- and sex-matched healthy subjects underwent a treadmill exercise test. Plasma BNP levels were measured sequentially before, immediately after, and 1 hour after the exercise test. Results: The mean plasma BNP +/- standard deviation levels of the COPD and control groups before exercise were 21.3 +/- 16 pg/ml and 13.4 +/- 11 pg/ml, respectively (P>0.05). Mean plasma BNP level measured immediately after exercise was 37.9 +/- 31 pg/ml in the COPD group, reflecting a statistically significant increase when compared with the initial value (P<0.05). The control group did not show any significant change in plasma BNP levels after the exercise test. Conclusion: Exercise induces an increase in plasma BNP levels in patients with COPD who do not have right ventricular dysfunction at rest. Measurement of exercise-induced BNP levels may be a useful alternative to pulmonary artery catheterisation in identifying the patients who are likely to benefit from long-term oxygen therapy.
dc.identifier.doi10.1007/s12325-008-0067-1
dc.identifier.endpage680
dc.identifier.issn0741-238X
dc.identifier.issn1865-8652
dc.identifier.issue7en_US
dc.identifier.pmid18563310
dc.identifier.scopus2-s2.0-58149352847
dc.identifier.scopusqualityQ1
dc.identifier.startpage674
dc.identifier.urihttps://doi.org/10.1007/s12325-008-0067-1
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8859
dc.identifier.volume25
dc.identifier.wosWOS:000258652800004
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGemici, Gökmen
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofAdvances in Therapy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectbrain natriuretic peptide
dc.subjectchronic obstructive pulmonary disease
dc.subjectright ventricle
dc.subjectObstructive Pulmonary-Disease
dc.subjectTerm Oxygen-Therapy
dc.subjectBrain
dc.subjectHemodynamics
dc.subjectHypertension
dc.subjectDysfunction
dc.subjectBenefits
dc.subjectAtrial
dc.titleB-type natriuretic peptide levels in patients with COPD and normal right ventricular function
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
8859.pdf
Boyut:
171.66 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu