Speckle-tracking strain assessment of left ventricular dysfunction in synthetic cannabinoid and heroin users

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dc.authorid0000-0002-6726-0478
dc.authorid0000-0001-8322-3514
dc.authorid0000-0002-6726-0478
dc.authorwosidZorkun, Cafer/Q-1247-2019
dc.authorwosidAlbayrak, Yakup/ABA-7651-2020
dc.authorwosiddemirkıran, aykut/AAE-1755-2021
dc.authorwosidDEMIRKIRAN, Aykut/AAC-8175-2021
dc.authorwosidZorkun, Cafer/S-7132-2016
dc.contributor.authorDemirkiran, Aykut
dc.contributor.authorAlbayrak, Neslihan
dc.contributor.authorAlbayrak, Yakup
dc.contributor.authorZorkun, Cafer Sadik
dc.date.accessioned2022-05-11T14:41:06Z
dc.date.available2022-05-11T14:41:06Z
dc.date.issued2018
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Ruh Sağlığı ve Hastalıkları Ana Bilim Dalı
dc.description.abstractObjective: There is growing evidence regarding the numerous adverse effects of synthetic cannabinoids (SCBs) on the cardiovascular system; however, no studies have shown the cardiovascular effects of opioids using strain echocardiography. This study examines the cardiac structure and function using echocardiographic strain imaging in heroin and synthetic cannabinoid users. Methods: This double-blind study included patients who were admitted or referred to a rehabilitation center for heroin (n=31) and synthetic cannabinoid users (n=30). Heroin users and synthetic cannabinoid users were compared with healthy volunteers (n=32) using two-dimensional (2D) speckle-tracking (ST) echocardiography. Results: No differences were found in the baseline characteristics and 2D echocardiography values. The mean global longitudinal strain value was -20.5%+/- 2.4% for SCB users, -22.3%+/- 2.4% for opioid users, and -22.5%+/- 2.2% for healthy volunteers (p=0.024). The mean apical 2-chamber (AP2C) L-strain values were -20.1%+/- 3.1%, -22.4%+/- 3.0%, and -22.3%+/- 2.8% for SCB users, opioid users, and healthy volunteers, respectively (p=0.032). The mean apical 4-chamber (AP4C) L-strain values were -20.7%+/- 2.5% for SCB users, -23.2%+/- 3.2% for opioid users, and -23.8%+/- 3.1% for healthy volunteers (p<0.001). Conclusion: SCBs are potential causes of subclinical left ventricular dysfunction.
dc.identifier.doi10.14744/AnatolJCardiol.2018.76429
dc.identifier.endpage393
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue6en_US
dc.identifier.pmid29848923
dc.identifier.startpage388
dc.identifier.urihttps://doi.org/10.14744/AnatolJCardiol.2018.76429
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9066
dc.identifier.volume19
dc.identifier.wosWOS:000435197200008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.institutionauthorAlbayrak, Yakup
dc.language.isoen
dc.publisherTurkish Soc Cardiology
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectstrain
dc.subjectleft ventricular function
dc.subjectsynthetic cannabinoid
dc.subjectheroin
dc.subjectMyocardial-Infarction
dc.subjectSystolic Function
dc.subjectReceptor
dc.subjectEchocardiography
dc.subjectDisease
dc.subjectAnalogs
dc.subjectCb2
dc.titleSpeckle-tracking strain assessment of left ventricular dysfunction in synthetic cannabinoid and heroin users
dc.typeArticle

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