Serum 25-hydroxyvitamin d levels and risk of incident heart failure in patients with newly diagnosed hypertension

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dc.authorid0000-0002-5340-4290
dc.authorwosidyücel, enver/AAD-3884-2020
dc.contributor.authorBoyuk, Banu
dc.contributor.authorBasmakci, Ayse
dc.contributor.authorYücel, Enver
dc.contributor.authorGüzel, Savaş
dc.contributor.authorKüçükyalçın, Volkan
dc.contributor.authorEkizoğlu, İsmail
dc.date.accessioned2022-05-11T14:42:05Z
dc.date.available2022-05-11T14:42:05Z
dc.date.issued2015
dc.departmentFakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı
dc.description.abstractBackround and aims: Both vitamin D deficiency and hypertension widely effects general population. The studies about the interaction between these two condition is intriguing. This study aims to determine the association between levels of 25-hydroxyvitamin D (25[OH]D) in the sera of newly diagnosed hypertension patients and risk of incident heart failure. Methods: We recruited 50 newly diagnosed hypertension patients and 20 healthy controls and assessed them for left ventricular diastolic dysfunction by echocardiography. Patient blood was tested for 25(OH)D concentrations. Patient group is divided into two subgroups: Group 1 subjects <20 ng/ml 25 OH D and Group 2 subjects >= 20 ng/ml 25(OH). Results: We found that serum 25(OH)D (ng/ml) levels of patient group were significantly lower than the control group (15.63 +/- 5.71; p<0.004). E/A, and diastolic diameter were significantly different (p<0.05) between the Group 1 and Group 2. EF, diastolic diameter, systolic diameter, systolic arterial pressure, and gender had significant effects on the multivariate model (p<0.05). Conclusion: Study results support the theory that vitamin D deficiency plays a role in the development of heart failure. Our study found a relationship between 25(OH)D vitamin levels and left ventricular diastolic dysfunction in newly diagnosed hypertension patients.
dc.identifier.endpage66
dc.identifier.issn0393-6384
dc.identifier.issn2283-9720
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84944277417
dc.identifier.scopusqualityN/A
dc.identifier.startpage61
dc.identifier.urihttps://hdl.handle.net/20.500.11776/9214
dc.identifier.volume31
dc.identifier.wosWOS:000346319200009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorGüzel, Savaş
dc.institutionauthorKüçükyalçın, Volkan
dc.language.isoen
dc.publisherCarbone Editore
dc.relation.ispartofActa Medica Mediterranea
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectvitamin D
dc.subjecthypertension
dc.subjectdiastolic dysfunction
dc.subjectVitamin-D Deficiency
dc.subject3rd National-Health
dc.subjectBlood-Pressure
dc.subjectParathyroid-Hormone
dc.subject1,25-Dihydroxyvitamin D-3
dc.subjectIntravenous Calcitriol
dc.subjectD Supplementation
dc.subjectHigh Prevalence
dc.subjectOlder Men
dc.subjectAssociation
dc.titleSerum 25-hydroxyvitamin d levels and risk of incident heart failure in patients with newly diagnosed hypertension
dc.typeArticle

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