Can the Glasgow prognostic score predict ischemic stroke in patients with infective endocarditis?

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dc.contributor.authorAydin, Cihan
dc.contributor.authorDemirkiran, Aykut
dc.contributor.authorAykac, Huseyin
dc.contributor.authorUslu, Nurullah
dc.contributor.authorAlpsoy, Seref
dc.date.accessioned2024-10-29T17:58:56Z
dc.date.available2024-10-29T17:58:56Z
dc.date.issued2024
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractOBJECTIVE: The Glasgow prognosis score is a simple parameter calculated using serum levels of albumin and C-reactive protein. The aim of this study was to examine whether this parameter may predict ischemic stroke in patients with infective endocarditis. METHODS: A total of 80 patients who were diagnosed with definitive infective endocarditis according to Duke criteria between 2016 and 2023 were included in the study. Glasgow prognosis score was based on serum levels of albumin and C-reactive protein. In imaging methods, patients were divided into two groups according to whether they had a stroke or not. These two groups were compared in terms of biochemical parameters, and infective endocarditis findings on echocardiography and Glasgow prognosis score. RESULTS: We found that the results were statistically similar except for serum C-reactive protein (Group 1: 54.9 +/- 71.1 and Group 2: 39 +/- 70.7; p=0.03), neutrophil (Group 1: 19.8 +/- 10.8*10(9)/L and Group 2: 13.3 +/- 7.3*109/L; p=0.014), albumin (Group 1: 2.3 +/- 0.6 and Group 2: 2.8 +/- 0.5; p=0.03), and Glasgow prognosis score (Group 1: median 2, min.-max. (1-2) and Group 2: median 1, min.-max. (0-1); p=0.004). In the receiver operating characteristics analysis, Glasgow prognosis score had 82.4% sensitivity and 58.3% specificity in predicting ischemic stroke if the Glasgow prognosis score cutoff was >= 1. In multivariate logistic regression analysis, chronic renal failure [odds ratio (OR): 1.098; 95% confidence interval: 1.054-1.964; p=0.044], age (OR: 1.050; 95%CI 1.006-1.096; p=0.024), and Glasgow prognosis score (OR: 0.695; 95%CI 0.411-0.949; p=0.035) were independent variables in predicting ischemic stroke. CONCLUSION: High Glasgow prognosis score is an independent predictor of ischemic stroke in patients with infective endocarditis. Glasgow prognosis score, determined using albumin and C-reactive protein levels, is a simple and practical index for predicting the prognosis of patients hospitalized with infective endocarditis.
dc.identifier.doi10.1590/1806-9282.20231299
dc.identifier.issn0104-4230
dc.identifier.issn1806-9282
dc.identifier.issue3en_US
dc.identifier.pmid38656008
dc.identifier.scopus2-s2.0-85191415206
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.1590/1806-9282.20231299
dc.identifier.urihttps://hdl.handle.net/20.500.11776/14561
dc.identifier.volume70
dc.identifier.wosWOS:001218392900001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAssoc Medica Brasileira
dc.relation.ispartofRevista Da Associacao Medica Brasileira
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPrognosis
dc.subjectTransesophageal echocardiography
dc.subjectC-reactive protein
dc.subjectAlbumin
dc.titleCan the Glasgow prognostic score predict ischemic stroke in patients with infective endocarditis?
dc.typeArticle

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