Synthesis of Novel Pyrrolo[3,2-c]carbazole and Dipyrrolo[3,2-c: 2 ',3 '-g]carbazole Derivatives

Basit Öğe Kaydı
dc.authorid0000-0002-7347-2223
dc.authorid0000-0001-9386-4892
dc.authorwosidk, h/ABA-1339-2020
dc.authorwosidSengul, Ibrahim Fazil/AAG-4368-2019
dc.contributor.authorŞengül, İbrahim Fazıl
dc.contributor.authorAstarcı, Erhan
dc.contributor.authorKandemir, Hakan
dc.date.accessioned2022-05-11T14:30:56Z
dc.date.available2022-05-11T14:30:56Z
dc.date.issued2016
dc.departmentFakülteler, Fen Edebiyat Fakültesi, Kimya Bölümü
dc.description.abstractPyrrolocarbazole and dipyrrolocarbazoles have been synthesized via the Hemetsberger indole synthesis, starting from 9-ethyl carbazole-3-carbaldehyde and 9-ethylcarbazole-3,6-dicarbaldeyde, respectively. The pyrrolocarbazole structures were confirmed through H-1 NMR, C-13 NMR, IR, mass spectrometry and single crystal X-ray diffraction techniques. The targeted compounds showed potent in vitro cytotoxicity against human colon cancer HT29 cells.
dc.description.sponsorshipTUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [113Z159]
dc.description.sponsorshipThis work was funded by TUBITAK grant 113Z159 to E.A., I.F.S., and H.K. We thank the NMR facility of Gebze Technical University.
dc.identifier.doi10.1055/s-0035-1560601
dc.identifier.endpage1281
dc.identifier.issn0936-5214
dc.identifier.issn1437-2096
dc.identifier.issue8en_US
dc.identifier.startpage1277
dc.identifier.urihttps://doi.org/10.1055/s-0035-1560601
dc.identifier.urihttps://hdl.handle.net/20.500.11776/7239
dc.identifier.volume27
dc.identifier.wosWOS:000375004700028
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.institutionauthorKandemir, Hakan
dc.language.isoen
dc.publisherGeorg Thieme Verlag Kg
dc.relation.ispartofSynlett
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectcarbazole
dc.subjectpyrrolocarbazole
dc.subjectHemetsberger indolization
dc.subjectHT29 cells
dc.subjectcyctotoxicity
dc.subjectInhibitors
dc.titleSynthesis of Novel Pyrrolo[3,2-c]carbazole and Dipyrrolo[3,2-c: 2 ',3 '-g]carbazole Derivatives
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
7239.pdf
Boyut:
1.15 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Fen Edebiyat Fakültesi Koleksiyonu