Evaluation of mean platelet volume as a diagnostic biomarker in acute appendicitis

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dc.authorid0000-0001-8707-5301
dc.authorid0000-0003-2006-9198
dc.authorid0000-0001-9111-2734
dc.authorscopusid36134374200
dc.authorscopusid12144383600
dc.authorscopusid24398544300
dc.authorscopusid14042203500
dc.authorscopusid57203303110
dc.authorscopusid8431600000
dc.authorscopusid35410250800
dc.authorwosidirkorucu, oktay/AAL-7383-2020
dc.authorwosidCetinkunar, Suleyman/AFP-2813-2022
dc.authorwosidSözen, Selim/ABA-6337-2020
dc.contributor.authorErdem, Hasan
dc.contributor.authorAktimur, Recep
dc.contributor.authorÇetinkunar, Süleyman
dc.contributor.authorReyhan, Enver
dc.contributor.authorGökler, Cihan
dc.contributor.authorIrkorucu, Oktay
dc.contributor.authorSözen, Selim
dc.date.accessioned2022-05-11T14:34:56Z
dc.date.available2022-05-11T14:34:56Z
dc.date.issued2015
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Genel Cerrahi Ana Bilim Dalı
dc.description.abstractBackground: Diagnosis of acute appendicitis remains to be challenging with up to 30% negative exploration rates. In addition to careful clinical history and physical examination, we still need easily applicable, cheap and effective biomarker. Patients and methods: A retrospective case-controlled study was designed in two groups, both containing 100 patients, acute appendicitis and control. Leukocyte count, neutrophil percentage, platelet count and meal platelet volume (MPV) were compared. Results: MPV values for acute appendicitis and control groups were 7.4 +/- 0.9 fL (5.6-10.6) and 9.1 +/- 1.6 fL (5.1-13.1). For the diagnosis of acute appendicitis, ROC analysis revealed 74% sensitivity and 75% specificity for a cut-off value of 7.95 fL of MPV, however, the diagnostic value of leukocyte count and/or neutrophil ratio was superior. Conclusion: Our results suggest that, MPV value is an important parameter in the diagnosis of acute appendicitis, but in terms of sensitivity and specificity, leukocyte count and/or neutrophil percentage is superior.
dc.identifier.endpage1295
dc.identifier.issn1940-5901
dc.identifier.issue1en_US
dc.identifier.pmid25785128
dc.identifier.scopus2-s2.0-84922998706
dc.identifier.scopusqualityN/A
dc.identifier.startpage1291
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8144
dc.identifier.volume8
dc.identifier.wosWOS:000349897200161
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorSözen, Selim
dc.language.isoen
dc.publisherE-Century Publishing Corp
dc.relation.ispartofInternational Journal of Clinical and Experimental Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAcute appendicitis
dc.subjectmean platelet volume
dc.subjectsensitivity
dc.subjectspecificity
dc.subjectInflammatory-Bowel-Disease
dc.subjectIndicator
dc.subjectAccuracy
dc.subjectMarker
dc.titleEvaluation of mean platelet volume as a diagnostic biomarker in acute appendicitis
dc.typeArticle

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