Contribution of nonattenuation-corrected images on FDG-PET/CT in the assessment of solitary pulmonary nodules

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dc.authorid0000-0002-3650-8258
dc.authorid0000-0002-3053-9133
dc.authorscopusid35949526800
dc.authorscopusid57190884913
dc.authorscopusid50461202500
dc.authorwosidELBOGA, UMUT/AAH-1320-2020
dc.authorwosidSahin, Ertan/AAG-8999-2020
dc.contributor.authorŞahin, Ertan
dc.contributor.authorKara, Ahmet
dc.contributor.authorElboğa, Umut
dc.date.accessioned2022-05-11T14:40:54Z
dc.date.available2022-05-11T14:40:54Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nükleer Tıp Ana Bilim Dalı
dc.description.abstractIn this study, we aim to determine the diagnostic performance of nonattenuation-corrected (NAC) and attenuation-corrected (AC) FDG-PET/CT images in the assessment of solitary pulmonary nodule (SPN). We reviewed the images of 41 patients who underwent FDG-PET/CT to diagnose SPNs. The visual analysis of FDG uptake intensity in SPN on AC and NAC PET images was made using a four-point score from 1 to 4 on both AC and NAC PET images. The cutoff value of SUVmax and visual uptake scores for malignancy were defined as >= 2.5 and >= 3, respectively. The significant visual uptake (>= 2 visual point score) on AC and NAC PET images was considered to be positive 18F-FDG PET findings for lesion detectability. The sensitivity, specificity and diagnostic accuracy were calculated for AC and NAC PET images. Based on the histopathology and imaging data, 22 of the SPNs (54 %) were malignant and 19 of them (46 %) were benign. The sensitivity and NPV were found to be 100 % in the detection of SPNs for AC and NAC PET images. For all SPNs and SPNs <= 2 cm, NAC PET image had a higher diagnostic performance for the SPN characterization as malignant or benign, when compared with AC PET image. The success rates of AC and NAC PET images were found to be similar for the detection of SPNs. NAC PET image had a higher diagnostic performance for the SPN characterization. It is thought that NAC PET image may provide additional contributions for characterization of SPNs.
dc.identifier.doi10.1007/s11547-016-0681-y
dc.identifier.endpage949
dc.identifier.issn0033-8362
dc.identifier.issn1826-6983
dc.identifier.issue12en_US
dc.identifier.pmid27567614
dc.identifier.scopus2-s2.0-84983762663
dc.identifier.scopusqualityQ1
dc.identifier.startpage944
dc.identifier.urihttps://doi.org/10.1007/s11547-016-0681-y
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8960
dc.identifier.volume121
dc.identifier.wosWOS:000392061200007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorŞahin, Ertan
dc.language.isoen
dc.publisherSpringer-Verlag Italia Srl
dc.relation.ispartofRadiologia Medica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectPET/CT
dc.subjectFDG
dc.subjectAttenuation corrected
dc.subjectSolitary pulmonary nodule
dc.subjectPositron-Emission-Tomography
dc.subjectAttenuation Correction
dc.subjectF-18-Fdg Pet
dc.subjectOncology
dc.subjectLesions
dc.subjectLymphoma
dc.titleContribution of nonattenuation-corrected images on FDG-PET/CT in the assessment of solitary pulmonary nodules
dc.typeArticle

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