Clinical and laboratory factors associated with bamboo spine in patients with axial spondyloarthritis: are there clues for bamboo spine?

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dc.authorscopusid6506828924
dc.authorscopusid7004353906
dc.authorscopusid7004438602
dc.authorscopusid14422446100
dc.authorscopusid37114171300
dc.authorscopusid57188850063
dc.authorscopusid55646165400
dc.contributor.authorAtagündüz, P.
dc.contributor.authorKiraz, S.
dc.contributor.authorAkar, S.
dc.contributor.authorKüçükşahin, O.
dc.contributor.authorErden, A.
dc.contributor.authorAksoy, A.
dc.contributor.authorCoşkun, B.N.
dc.contributor.authorMercan, Rıdvan
dc.date.accessioned2023-05-06T17:23:32Z
dc.date.available2023-05-06T17:23:32Z
dc.date.issued2023
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.description.abstractObjective To analyse the clinical and laboratory factors associated with bamboo spine. Methods Data of patients fulfilling the 2009 ASAS classification criteria for axial spondyloarthritis, registered in the national, multicentre, longitudinal, and observational database of TReasure was analysed. Radiographs were assessed using the Bath Ankylosing Spondylitis Radiologic Index (BASRI). Data of patients with a bamboo spine (Group 1) was compared to data derived from patients with a longstanding disease of at least 15 years but no syndesmophytes (Group 2). Results Out of the 5060 patients, 1246 had eligible radiographs. There were 111 patients (8.9%) with a bamboo spine. Male sex was more common among patients with bamboo spine. The median BMI of 27.7 (25.8-31.1) in Group1 was higher than the BMI of 25.9 (22.9-29.2) in Group 2 (p<0.001). Hip arthritis, present or documented by a physician, was more common in Group 1 [(58/108 (53.7%) vs. 35/103 (34%), p=0.004]. There was a tendency towards a more prevalent enthesitis in these patients [29.1% (25/86) vs. 15.9%(11/69), p=0.054]. HLA-B27 status did not differ between groups. Smoking was more prevalent in Group 1. Multivariate logistic regression analysis revealed that male sex, body mass index, hip arthritis, and enthesitis are associated with bamboo spine in axSpA. Conclusion Bamboo spine was more common in the male sex and associated with a delay in diagnosis, high BMI, hip involvement, and enthesitis. The constellation of increased body weight, hip arthritis, and enthesitis may imply that mechanical stress contributes to radiographic damage in the presence of chronic inflammation. © Copyright CliniCal and ExpErimEntal rhEumatology 2023.
dc.description.sponsorshipEthics approval: ethics committee approval for the use of the TReasure database was obtained from Hacettepe University (KA-17/058) in May 2017 and from the Ministry of Health-Turkey (93189304-14.03.01) in October 2017. Written informed consent form was obtained from all participants. Funding: this study was funded by the Hacettepe Rheumatology Society. Competing interests: P. Atagunduz received honoraria from Abbvie, Johnson and Johnson, MSD, Novartis, Pfizer, Roche, and UCB. The other authors have declared no competing interests.
dc.identifier.doi10.55563/clinexprheumatol/eb1zpo
dc.identifier.endpage627
dc.identifier.issn0392-856X
dc.identifier.issue3en_US
dc.identifier.pmid35766019
dc.identifier.scopus2-s2.0-85151044605
dc.identifier.scopusqualityQ2
dc.identifier.startpage620
dc.identifier.urihttps://doi.org/10.55563/clinexprheumatol/eb1zpo
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12128
dc.identifier.volume41
dc.identifier.wosWOS:001111723800010
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorMercan, Rıdvan
dc.language.isoen
dc.publisherClinical and Experimental Rheumatology S.A.S.
dc.relation.ispartofClinical and Experimental Rheumatology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectaxial spondyloarthritis
dc.subjectbamboo spine
dc.subjectbody mass index
dc.subjectenthesitis
dc.subjecthip arthritis
dc.subjectankylosing spondylitis
dc.subjectcomplication
dc.subjectdiagnostic imaging
dc.subjectenthesopathy
dc.subjecthuman
dc.subjectmale
dc.subjectradiography
dc.subjectsmoking
dc.subjectspine
dc.subjectspondylarthritis
dc.subjectspondyloarthropathy
dc.subjectEnthesopathy
dc.subjectHumans
dc.subjectMale
dc.subjectRadiography
dc.subjectSmoking
dc.subjectSpine
dc.subjectSpondylarthritis
dc.subjectSpondylarthropathies
dc.subjectSpondylitis, Ankylosing
dc.titleClinical and laboratory factors associated with bamboo spine in patients with axial spondyloarthritis: are there clues for bamboo spine?
dc.typeArticle

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