Relationship between uric acid/ albumin ratio and coronary slow flow

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dc.contributor.authorDemirkıran, Aykut
dc.contributor.authorAydın, Cihan
dc.date.accessioned2024-10-29T17:50:02Z
dc.date.available2024-10-29T17:50:02Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesien_US
dc.description.abstractObjectives: Although the pathophysiology of coronary slow flow is not fully understood, evidence suggesting endothelial dysfunction and subclinical widespread atherosclerosis in genesis has grown in recent years. Our aim in this study is to investigate the relationship between uric acid/ albumin ratio and coronary slow flow. Methods: One hundred and five coronary slow flow patients (determined by the Thrombolysis in Myocardial Infarction-frame count method) and one-hundred patients with normal coronary low were included retrospectively. The uric acid/ albumin ratio was investigated in all patients participating. Results: In the logistic regression analysis, it was revealed that high uric acid levels, uric acid/ albumin ratios, and male gender were independent predictors for coronary slow flow. Among these parameters, the uric acid/ albumin ratio was the best predictor of coronary slow flow. Based on the receiver operating characteristics (ROC) analysis, the cut-off value of uric acid/ albumin ratio ? 0.57 was found to predict coronary slow flow with 68.3% sensitivity and 68.7% specificity. In multivariate logistic regression analysis, high uric acid levels (OR: 2.22; 95% CI (1.551-3.200), p < 0.001), high serum uric acid/ albumin ratio (OR: 37.7 95% CI (8.176-234.387), p < 0.001), male gender (OR: 0.157; 95% CI (0.078-0.318), p < 0.001) were independent predictors of coronary slow flow. Conclusions: High uric acid/ albumin ratio was detected as an independent predictor for coronary slow flow. Larger studies are needed to elucidate its role in the pathophysiology of coronary slow flow.en_US
dc.identifier.doi10.18621/eurj.1340527
dc.identifier.endpage1177en_US
dc.identifier.issn2149-3189
dc.identifier.issue5en_US
dc.identifier.startpage1171en_US
dc.identifier.trdizinid1194893en_US
dc.identifier.urihttps://doi.org/10.18621/eurj.1340527
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1194893
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12733
dc.identifier.volume9en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofThe European Research Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectUric aciden_US
dc.subjectcoronary slow flowen_US
dc.subjecturic acid/ albumin ratioen_US
dc.titleRelationship between uric acid/ albumin ratio and coronary slow flowen_US
dc.typeArticleen_US

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