Biosensor approaches on the diagnosis of neurodegenerative diseases: Sensing the past to the future

dc.authorscopusid56800873300
dc.authorscopusid6506764918
dc.contributor.authorKaraboğa, Munteha Nur Sonuç
dc.contributor.authorSezgintürk, Mustafa Kemal
dc.date.accessioned2022-05-11T14:07:28Z
dc.date.available2022-05-11T14:07:28Z
dc.date.issued2022
dc.departmentYüksekokullar, Sağlık Yüksekokulu, Beslenme ve Diyetetik Bölümü
dc.description.abstractEarly diagnosis of neurodegeneration-oriented diseases that develop with the aging world is essential for improving the patient's living conditions as well as the treatment of the disease. Alzheimer's and Parkinson's diseases are prominent examples of neurodegeneration characterized by dementia leading to the death of nerve cells. The clinical diagnosis of these diseases only after the symptoms appear, delays the treatment process. Detection of biomarkers, which are distinctive molecules in biological fluids, involved in neurodegeneration processes, has the potential to allow early diagnosis of neurodegenerative diseases. Studies on biosensors, whose main responsibility is to detect the target analyte with high specificity, has gained momentum in recent years with the aim of high detection of potential biomarkers of neurodegeneration process. This study aims to provide an overview of neuro-biosensors developed on the basis of biomarkers identified in biological fluids for the diagnosis of neurodegenerative diseases such as Alzheimer's disease (AD), and Parkinson's disease (PD), and to provide an overview of the urgent needs in this field, emphasizing the importance of early diagnosis in the general lines of the neurodegeneration pathway. In this review, biosensor systems developed for the detection of biomarkers of neurodegenerative diseases, especially in the last 5 years, are discussed. © 2021 Elsevier B.V.
dc.identifier.doi10.1016/j.jpba.2021.114479
dc.identifier.issn0731-7085
dc.identifier.pmid34861607
dc.identifier.scopus2-s2.0-85120160116
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1016/j.jpba.2021.114479
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5116
dc.identifier.volume209
dc.identifier.wosWOS:000736852300004
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKaraboğa, Munteha Nur Sonuç
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofJournal of Pharmaceutical and Biomedical Analysis
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectbiological marker
dc.subjectAlzheimer disease
dc.subjectdegenerative disease
dc.subjectgenetic procedures
dc.subjecthuman
dc.subjectParkinson disease
dc.subjectAlzheimer Disease
dc.subjectBiomarkers
dc.subjectBiosensing Techniques
dc.subjectHumans
dc.subjectNeurodegenerative Diseases
dc.subjectParkinson Disease
dc.titleBiosensor approaches on the diagnosis of neurodegenerative diseases: Sensing the past to the future
dc.typeReview Article

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