Evaluation of mechanical prosthetic valves: the role of three dimensional echocardiography in calculating effective orifice area in obese vs non-obese individuals

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dc.authorscopusid55317577700
dc.authorscopusid53663196500
dc.authorscopusid10139012600
dc.authorscopusid6505680586
dc.authorscopusid16315021800
dc.authorscopusid14008084500
dc.authorwosidGurkan, Selami/AAA-9006-2022
dc.authorwosidBaykız, Derya/ABD-7865-2020
dc.authorwosidgur, ozcan/AAA-8847-2022
dc.contributor.authorÖzkaramanlı Gür, Demet
dc.contributor.authorBaykiz, Derya
dc.contributor.authorGür, Özcan
dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorAkyüz, Aydın
dc.contributor.authorGürkan, Selami
dc.date.accessioned2022-05-11T14:12:28Z
dc.date.available2022-05-11T14:12:28Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.description.abstractCalculation of effective orifice area (EOA) is crucial for the evaluation of prosthetic valve (PV) function and there is lack of data on the best method, particularly in obese patients, in whom two-dimensional (2D) transthoracic echocardiography (TTE) is cumbersome. We sought to compare two methods of calculating EOA through Continuity equation; one using standard 2D-TTE and other three-dimensional (3D) stoke volume (SV), in patients with bileaflet mechanical PV stratified by body mass index (BMI). On conventional TTE, SV mas measured using standard 2D derived data and 3D derived SV in 38 aortic and 62 mitral PV patients who were referred for further evaluation for mild/moderate symptoms of dyspnea. Patients were categorized with regard to transprosthetic flow into 'normal-flow' and 'high-flow' groups and several echocardiographic data including 2D and 3D EOA were compared. Rates of obesity (BMI >= 30) were similar within high and normal flow groups of mitral and aortic PV patients. Correlation and agreement of 2D and 3D EOA was sought in patients with and without obesity. After identifying patients with possible severe obstruction, ROC analysis was carried out to identify whether 2D and 3D derived EOA could discriminate those with obstruction. There was good correlation and agreement between two methods in patients without obesity in both mitral and aortic PV. In obese individuals, however, there was no correlation between 2D and 3D EOA; in whom echocardiographic criteria showing severe obstruction revealed that 3D EOA measurements were more accurate. ROC analysis supported that 3D EOA performs better to identify patients with obstructive characteristics. In patients with bileaflet PV, measurement of EAO by 3D derived SV yields more accurate results irrespective of BMI.
dc.identifier.doi10.1007/s10554-020-01978-3
dc.identifier.endpage227
dc.identifier.issn1569-5794
dc.identifier.issn1573-0743
dc.identifier.issue1en_US
dc.identifier.pmid32833185
dc.identifier.scopus2-s2.0-85089746874
dc.identifier.scopusqualityQ2
dc.identifier.startpage215
dc.identifier.urihttps://doi.org/10.1007/s10554-020-01978-3
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5570
dc.identifier.volume37
dc.identifier.wosWOS:000562338500001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzkaramanlı Gür, Demet
dc.institutionauthorGür, Özcan
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorAkyüz, Aydın
dc.institutionauthorGürkan, Selami
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofInternational Journal of Cardiovascular Imaging
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectProsthetic valve
dc.subjectEffective orifice area
dc.subjectObesity
dc.subjectThree dimensional echocardiography
dc.subjectVentricular Outflow Tract
dc.subjectEuropean Association
dc.subjectAmerican Society
dc.subjectEae/Ase Recommendations
dc.subjectDoppler Ultrasound
dc.subjectHeart-Association
dc.subjectAortic-Stenosis
dc.subjectTask-Force
dc.subjectGuidelines
dc.subjectAgreement
dc.titleEvaluation of mechanical prosthetic valves: the role of three dimensional echocardiography in calculating effective orifice area in obese vs non-obese individuals
dc.typeArticle

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