The clinical significance of abnormal ejaculation by silodosin. Is it important?
Yükleniyor...
Dosyalar
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Blackwell Publishing Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
We aimed to evaluate the effect of the abnormal ejaculation (AEj) on patients using silodosin in terms of drug cessation. We also analysed the possible factors that may affect the decisions of patients with AEj to proceed or change their medication. The patients (n = 118) treated with silodosin 8 mg daily were prospectively analysed. In order to evaluate the erectile function, ejaculatory function, depression and sexual satisfaction; IIEF, MSHQ-EjD, Beck's depression and Golombok-Rust questionnaires were given to patients respectively. Patients were re-evaluated at the 3rd month of their treatment. The rate of AEj was 52.5%. Nearly 42% of the patients with AEj desired to stop their medication whereas it was 7.1% at patients without AEj (p <.001). The pre-treatment International Prostate Symptom Score (IPSS) and the decrease in IPSS score were significantly lower in patients who demand to stop their treatment (p <.05). AEj was significantly higher in patients who wanted to stop their medication (p <.001). Even if they had an AEj, patients who were happy with the clinical efficacy of silodosin did not want to change their drug. In addition to this, pre-treatment ejaculatory status was an important indicator for patients to decide drug cessation due to AEj side effect of silodosin. © 2021 Wiley-VCH GmbH.
Açıklama
Anahtar Kelimeler
abnormal ejaculation, benign prostate hyperplasia, silodosin, ?-blockers, silodosin, indole derivative, silodosin, adult, age, Article, clinical effectiveness, controlled study, depression assessment, domestic partnership, drug choice, drug efficacy, drug withdrawal, educational status, ejaculation, ejaculation disorder, family planning, human, incidence, International Index of Erectile Function, International Prostate Symptom Score, lower urinary tract symptom, major clinical study, male, marriage, masturbation, medical decision making, middle aged, molecular therapy, patient decision making, patient health questionnaire, penis erection, prospective study, prostate hypertrophy, prostate volume, sexual behavior, sexual health, sexual intercourse, sexual satisfaction, treatment interruption, treatment planning, treatment switching, treatment withdrawal, visual analog scale, lower urinary tract symptom, prostate hypertrophy, treatment outcome, Ejaculation, Humans, Indoles, Lower Urinary Tract Symptoms, Male, Prostatic Hyperplasia, Treatment Outcome
Kaynak
Andrologia
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
53
Sayı
7