To Save or not to Save the Kidney: Relieving Unilateral Obstruction May Significantly Improve an Initially Low Split Renal Creatinine Clearance

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dc.authorid0000-0003-0956-7460
dc.authorid0000-0001-6140-5181
dc.authorwosidTAVUKÇU, HASAN HÜSEYİN HHT/S-9943-2018
dc.authorwosidTAVUKÇU, HASAN HÜSEYİN/ABC-5055-2020
dc.authorwosidYazici, Cenk Murat/AAA-4330-2020
dc.contributor.authorYazıcı, Cenk Murat
dc.contributor.authorTavukçu, Hasan Hüseyin
dc.contributor.authorTinay, İlker
dc.contributor.authorTarcan, Tufan
dc.date.accessioned2022-05-11T14:36:59Z
dc.date.available2022-05-11T14:36:59Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı
dc.description.abstractObjective The aim of this study was to evaluate the change in acute/subacute unilateral renal function after the relief of complete unilateral ureteral obstruction by nephrostomy. Materials and Methods Thirty patients were prospectively enrolled in the study. All had ureteral stone, which were located in the upper ureter in 24 (80%) and in the middle ureter in 6 (20%) patients. As all patients had high-grade hydronephrosis, a percutaneous nephrostomy catheter was placed for the relief of obstruction. At the first week of urinary diversion, 24-hour creatinine clearance (CC) of both affected and normal kidneys were evaluated. In order to determine the difference, same evaluation was performed on the fourth week of nephrostomy placement. Results The mean age of the patients was 44.6 (36-54) years. The mean CC of the affected kidney was 38.8 similar to 4.9 ml/min in the first week of urinary diversion and increased to 42.5 similar to 5.4 ml/min at the end of the fourth week (p<0.001). All patients showed an improvement in CC levels ranging between 2.3% and 17.3% with a mean rate of 8.5 similar to 4.7%. Conclusion According to our results, kidney function may improve during the first month after the relief of obstruction. This improvement may be significant for borderline renal function to determine the curative treatment of an obstructed kidney
dc.identifier.doi10.4274/jus.2015.613
dc.identifier.endpage12
dc.identifier.issn2148-9580
dc.identifier.issue1en_US
dc.identifier.startpage7
dc.identifier.urihttps://doi.org/10.4274/jus.2015.613
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8519
dc.identifier.volume3
dc.identifier.wosWOS:000374666400002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.institutionauthorYazıcı, Cenk Murat
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofJournal of Urological Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCreatinine clearance
dc.subjectnephrostomy
dc.subjectobstructive uropathy
dc.subjectUreteropelvic Junction Obstruction
dc.subjectUrinary-Tract Obstruction
dc.subjectUreteral Obstruction
dc.subjectRecoverability
dc.subjectUropathy
dc.subjectPrediction
dc.subjectRecovery
dc.subjectRepair
dc.titleTo Save or not to Save the Kidney: Relieving Unilateral Obstruction May Significantly Improve an Initially Low Split Renal Creatinine Clearance
dc.typeArticle

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