Investigation of the Relationship Between Triglycerides-Glucose Index and Coronary Slow Flow: A Retrospective Case-Control Study

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dc.authoridAydin, Cihan/0000-0002-1401-5727
dc.authoridPalice, Ali/0000-0001-6560-8031
dc.authoridCekici, Yusuf/0000-0002-4585-3707
dc.authoridtoprak, kenan/0000-0001-8923-8709
dc.authoridBasanalan, Fuat/0000-0001-8358-722X
dc.authoridKaplangoray, Mustafa/0000-0002-4297-1820
dc.contributor.authorKaplangoray, Mustafa
dc.contributor.authorToprak, Kenan
dc.contributor.authorBasanalan, Fuat
dc.contributor.authorPalice, Ali
dc.contributor.authorAydin, Cihan
dc.contributor.authorDemirkiran, Aykut
dc.contributor.authorCekici, Yusuf
dc.date.accessioned2024-10-29T17:59:29Z
dc.date.available2024-10-29T17:59:29Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractBackground: Coronary slow flow (CSF) refers to delayed distal vessel opacification in the absence of epicardial coronary artery stenosis. The etiopathogenic mechanism of CSF is still unclear.Objectives: This study investigates the relationship between CSF and the triglyceride-glucose (TyG) index.Methods: The study sample consisted of 118 CSF patients and 105 patients with normal coronary flow (NCF). The coronary flow rate was measured via the Thrombolysis in Myocardial Infarction (TIMI) frame count (TFC) method in all patients. The TyG index was calculated as the logarithm of the [fasting triglyceride (mg/dL)xfasting glucose (mg/dL)]/2 value. A significance level of < 0.05 was adopted as statistically significant.Results: The TyG index, low-density lipoprotein (LDL), body mass index (BMI), neutrophil-to-lymphocyte ratio (NLR) and TFC values, male ratio, and the ratio of smokers were higher, whereas high-density lipoprotein (HDL) levels were significantly lower in the CSF group compared to the NCF group (p<0,05). The correlation analysis revealed that CSF was significantly correlated with TyG index, BMI, NLR, and HDL values. The strongest of these correlations was between CSF and TyG index (r= 0.57, p<0.001). Additionally, the multivariate analysis revealed that TyG index, BMI, NLR ratio, and male gender were independent predictors for CSF (p<0.05). Receiver operating characteristic (ROC) curve analysis indicated that a cut-off value of >= 9.28 for the TyG index predicted CSF with a sensitivity of 78% and a specificity of 78.1% [Area under the curve (AUC): 0.868 and 95% Confidence Interval (CI): 0.823-0.914].Conclusion: The findings of this study revealed a very strong relationship between CSF and TyG index.
dc.identifier.doi10.36660/abc.20220679
dc.identifier.issn0066-782X
dc.identifier.issn1678-4170
dc.identifier.issue6en_US
dc.identifier.pmid37255136
dc.identifier.scopus2-s2.0-85160640078
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.36660/abc.20220679
dc.identifier.urihttps://hdl.handle.net/20.500.11776/14751
dc.identifier.volume120
dc.identifier.wosWOS:001007042200001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherArquivos Brasileiros Cardiologia
dc.relation.ispartofArquivos Brasileiros De Cardiologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCoronary Artery Disease
dc.subjectBlood Flow Velocity
dc.subjectTriglicerideos-Glucose
dc.subjectLipoproteins
dc.subjectLDL
dc.subjectMyocardial Ischemic
dc.titleInvestigation of the Relationship Between Triglycerides-Glucose Index and Coronary Slow Flow: A Retrospective Case-Control Study
dc.typeArticle

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