Anticholinesterase, Antidiabetic and Antioxidant Activities of Chloroform Extract of Genista carinalis

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dc.contributor.authorÇalışkan, Hilmican
dc.contributor.authorOrak, Hakime Hülya
dc.contributor.authorCakır, Cansel
dc.contributor.authorArgon, Merve
dc.contributor.authorŞabudak, Temine
dc.contributor.authorÖztürk, Mehmet
dc.contributor.authorGüler, Necmettin
dc.date.accessioned2025-04-06T12:12:24Z
dc.date.available2025-04-06T12:12:24Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.descriptionNKUBAP.01.DR.22.352
dc.description.abstractAlzheimer's disease, diabetes has become an increasing public health issues in recent years. On the other hand, synthetic drugs are expensive, could be inadequate to treat diseases, could be cause irritation, and side effects. Therefore, increasingly more researchis being done to plant-derived formulas, bioactive ingredients, which can be an alternative to synthetic drugs for treatments to solve basic health problems. In this study the antioxidant, anticholinesterase and antidiabetic activities of G. carinalis in the chloroform extract were determined. Based on the results, the extract was not observed inhibitory activities of α-glucosidase and α-amylase. It showed better activity for acetylcholiesterase activity than the butylrylcholinesterase activity. The antioxidant potential of G. carinalis chloroform extract was determined with different assays. The TEAC value was determined to be 0.484 mmol TE/g, FRAP value was found to be 1023.20 µmol Fe2+/g for G. carinalis chloroform extract. The EC50 value of DPPH assays for extract was found to be 0.101 μg/ml.
dc.description.sponsorshipScientific Research Projects Coordination Unit of Tekirdag Namik Kemal University
dc.identifier.doi10.38093/cupmap.1229198
dc.identifier.issn2619-9645
dc.identifier.issn2667-5722
dc.identifier.issue1
dc.identifier.startpage6-Jan
dc.identifier.urihttps://hdl.handle.net/20.500.11776/16010
dc.identifier.urihttps://doi.org/10.38093/cupmap.1229198
dc.identifier.urihttps://dergipark.org.tr/tr/pub/cupmap/issue/77265/1229198
dc.identifier.volume6
dc.language.isoen
dc.publisherNazım ŞEKEROĞLU
dc.relation.ispartofCurrent Perspectives on Medicinal and Aromatic Plants
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_DergiPark_20250406
dc.subjectGenista
dc.subjectG. carinalis
dc.subjectAnticholinesterase activity
dc.subjectButyrylcholinesterase activity
dc.subjectTEAC
dc.subjectα-Amylase.
dc.titleAnticholinesterase, Antidiabetic and Antioxidant Activities of Chloroform Extract of Genista carinalis
dc.typeResearch Article

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