The Effect of Epidural Analgesia Added to General Anesthesia on Systemic Immune-Inflammation Index in Radical Prostatectomy Surgery: A Retrospective Study

dc.authoridGultekin, Ahmet/0000-0003-4570-8339
dc.authorscopusid56410672800
dc.authorscopusid57207998379
dc.authorscopusid36151868000
dc.authorscopusid55216749400
dc.authorscopusid57744470500
dc.authorscopusid56715452900
dc.authorscopusid6602393555
dc.contributor.authorGültekin, A.
dc.contributor.authorŞahin, A.
dc.contributor.authorAkgül, Murat
dc.contributor.authorYıldırım, I.
dc.contributor.authorAltınöz, K.
dc.contributor.authorBaran, O.
dc.contributor.authorArar, Cavidan
dc.date.accessioned2023-04-20T08:01:14Z
dc.date.available2023-04-20T08:01:14Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı
dc.description.abstractBackground: Systemic immune-inflammation index (SII) is increasingly valued for its simplicity and predictability. Anesthesia/analgesia technique may affect cancer survey. Aims: The primary aim of this study is to offer a comparative evaluation for the effect of different anesthesia/analgesia techniques employed in radical prostatectomy surgery on SII, a new inflammatory index. Patients and Methods: Eighty-one patients who underwent radical prostatectomy between January 1, 2012, and December 31, 2020, were included in the study. We recorded oncological demographic data of Group G (n = 45) and Group GE (n = 36), preoperative and postoperative (within the first 4 hrs and 24th hr) SII values, perioperative surgical bleeding, and amount of blood transfusion. Results: Despite the lack of significant difference in the SII values between the groups, both the peak SII level and the SII change in the postoperative period became higher in Group G than in Group GE. In addition, the amount of surgical bleeding and blood transfusion was observed to be significantly lower in Group GE (P < 0.001, P = 0.092, respectively). Conclusions: GE in radical prostatectomy surgery in terms of SII, the SII change in the postoperative period was more pronounced in Group G. However, a significant difference was noted in surgical bleeding in Group GE. We can conclude that comparing the SII values of different anesthesia techniques with prospective studies might thus create a difference in survival and metastasis at the micro-level.
dc.identifier.doi10.4103/njcp.njcp_1858_21
dc.identifier.endpage860
dc.identifier.issn1119-3077
dc.identifier.issue6en_US
dc.identifier.pmid35708428
dc.identifier.scopus2-s2.0-85132081948
dc.identifier.scopusqualityQ3
dc.identifier.startpage855
dc.identifier.urihttps://doi.org/10.4103/njcp.njcp_1858_21
dc.identifier.urihttps://hdl.handle.net/20.500.11776/10817
dc.identifier.volume25
dc.identifier.wosWOS:000813517100015
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorGültekin, A.
dc.institutionauthorŞahin, A.
dc.institutionauthorAkgül, Murat
dc.institutionauthorYıldırım, I.
dc.institutionauthorAltınöz, K.
dc.institutionauthorBaran, O.
dc.institutionauthorArar, Cavidan
dc.language.isoen
dc.publisherWolters Kluwer Medknow Publications
dc.relation.ispartofNigerian Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectEpidural Analgesia
dc.subjectRadical Prostatectomy
dc.subjectSystemic Immune-Inflammation Index
dc.subjectCancer Recurrence
dc.subjectRegional Anesthesia
dc.subjectBlood-Loss
dc.subjectSurvival
dc.titleThe Effect of Epidural Analgesia Added to General Anesthesia on Systemic Immune-Inflammation Index in Radical Prostatectomy Surgery: A Retrospective Study
dc.typeArticle

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