The Diagnosis of Multiple Myeloma With Macroglossia and Edema Symptoms

dc.contributor.authorKara, Sonat Pınar
dc.contributor.authorTekinalp, Atakan
dc.contributor.authorBilir, Bülent
dc.contributor.authorAvcı, Okan
dc.contributor.authorÖznur, Meltem
dc.contributor.authorTurgut, Burhan
dc.contributor.authorDeğirmenci, Hasan
dc.date.accessioned2022-05-11T14:10:06Z
dc.date.available2022-05-11T14:10:06Z
dc.date.issued2017
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractIn this case, the importance of multiple myeloma in differential diagnosis of non-specific symptoms, such as macroglossia and significant pretibial edema, is highlighted. A 44-year-old male presented to the internal medicine outpatient clinic with complaints of ongoing and increasing enlargement of the tongue, difficulty in swallowing, and swelling of legs, all of which had been occurring for 6 months. In the CT scan, significant symmetrical enlargement of the tongue was detected. Making a pre-diagnosis of amyloidosis, a biopsy of the tongue was performed, but the results did not suggest amyloidosis. A rectal biopsy was therefore subsequently performed, and this time the results showed amyloid accumulation. Findings from the transthoracic echocardiography showed an ejection fraction of 48%, contrast hypertrophy in the left ventricle, Grade 3 diastolic dysfunction, 15–19 ml of pericardial fluid around the heart, and mild mitral failure. Taking into consideration the pathological and cardiologic findings, the patient was diagnosed with amyloidosis. Bearing in mind the possible relation between primary hematologic malignancy and amyloidosis, a bone marrow aspiration and a bone marrow biopsy were performed. From the results of the biopsy and aspiration of bone marrow, the patient was diagnosed with multiple myeloma and treatment plans were made accordingly. However, as the patient was in the process of undergoing treatment he died due to the development of cardiopulmonary failure
dc.identifier.endpage56
dc.identifier.issn2587-0998
dc.identifier.issn2587-1404
dc.identifier.issue1en_US
dc.identifier.startpage53
dc.identifier.trdizinidTWpZMU9EazRPQT09
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpZMU9EazRPQT09
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5283
dc.identifier.volume28
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorTekinalp, Atakan
dc.institutionauthorTurgut, Burhan
dc.language.isoen
dc.relation.ispartofSouthern Clinics of Istanbul Eurasia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGenel ve Dahili Tıp
dc.titleThe Diagnosis of Multiple Myeloma With Macroglossia and Edema Symptoms
dc.typeArticle

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