The Relationship between Nifedipine and Postpartum Blood Loss in Patients with Preterm Labor

Basit Öğe Kaydı
dc.authoridAYDlN, Alev/0000-0001-9999-3273
dc.authoridUstun, Batuhan/0000-0002-2113-1232
dc.contributor.authorKiyak, Huseyin
dc.contributor.authorKorkmaz, Nazli
dc.contributor.authorCaypinar, Sema Suzen
dc.contributor.authorAcar, Zuat
dc.contributor.authorAydin, Alev Atis
dc.contributor.authorUstun, Batuhan
dc.contributor.authorAytufan, Zubeyde
dc.date.accessioned2024-10-29T17:59:08Z
dc.date.available2024-10-29T17:59:08Z
dc.date.issued2023
dc.departmentTekirdağ Namık Kemal Üniversitesi
dc.description.abstractBackground: The purpose of the study, to determine whether exposure to nifedipine before delivery is associated with an increased risk of postpartum blood loss in patients with preterm labor. Methods: This was a retrospective study screening a total of 486 patients who were admitted due to preterm labor from 2012 to 2019. Patients who were given nifedipine for tocolysis before delivery were considered as the study group (n: 240), and the patients who gave birth without getting tocolysis were considered as the control group (n: 246). The dose of nifedipine used during the last 24 hours, 72 hours and 1 week before delivery, the total dose of nifedipine given and the duration from the last dose to the delivery were recorded separately. Hemoglobin and hematocrit and platelet values measured before and 6 hours after delivery were recorded and postpartum bleeding amount was calculated. Results: No significant difference is observed in terms of mean difference between pre/postpartum hemoglobin and hematocrit levels between control group and nifedipine group (p > 0.05). But when subgroups that are created according to the time of use of nifedipine before delivery, a positive correlation was observed between difference in hemoglobin and hematocrit levels between prepartum and postpartum and nifedipine dosage for the last 24 hours (r = 0.176, p = 0.006), (r = 0.139, p = 0.030), but not for 72 hours or one week. Conclusions: The use of nifedipine in patients with preterm labor for tocolysis may be associated with increase in postpartum blood loss in the last 24 hours before delivery.
dc.identifier.doi10.31083/j.ceog5011225
dc.identifier.issn0390-6663
dc.identifier.issn2709-0094
dc.identifier.issue11en_US
dc.identifier.scopus2-s2.0-85176313825
dc.identifier.scopusqualityQ4
dc.identifier.urihttps://doi.org/10.31083/j.ceog5011225
dc.identifier.urihttps://hdl.handle.net/20.500.11776/14641
dc.identifier.volume50
dc.identifier.wosWOS:001124027100012
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherImr Press
dc.relation.ispartofClinical and Experimental Obstetrics & Gynecology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectnifedipine
dc.subjectpostpartum hemorrhage
dc.subjectpreterm labor
dc.subjectcalcium channel blockers
dc.titleThe Relationship between Nifedipine and Postpartum Blood Loss in Patients with Preterm Labor
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu