infection and vaccination status of children aged 6 months-12 years: Time for mass vaccination

Küçük Resim Yok

Tarih

2013

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Kowsar Medical Publishing Company

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Objective: This study was designed to determine the current age-related hepatitis A virus (HAV) seroprevalance, vaccination status of children and to evaluate the epidemiological shift in HAV serostatus living in Tekirda?, which is located in Thrace region, the European part of Turkey. Methods: Children 6 months-12 years of age with simple health problems were included. Blood samples were studied for HAV IgM and IgG collectively. A questionnaire addressing several characteristics of subjects was administered to obtain basic descriptive data on HAV epidemiology. Vaccination status of the children was recorded according to the immunization cards. Findings: The overall anti-HAV IgM and anti-HAV IgG prevalance in children aged 6 months - 12 years was 3.3% and 25.4% respectively. Maximum hepatitis A IgM positivity was in the 7-12 years age group 4.8% (n= 12; P<0.001) and maximum hepatitis A IgG positivity in the same age group was 34% (n=85; P<0.001). HAV vaccination rate among patients aged more than 2 years was 11.03%. HAV IgG seroprevalance was higher in children of low monthly income families (36.1%, n=78; P<0.001) than in the intermediate (17%, n=31) and high income families (11.1%, n=6). Conclusion: These results indicate a shift in Hepatitis A seroprevalance when compared with the previous studies. As HAV infection in childhood is decreasing, the pool of susceptible adolescents and young adults is increasing. Introduction of hepatitis A vaccination into the national immunization schedule of Turkey should be considered. © 2013 by Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, All rights reserved.

Açıklama

Anahtar Kelimeler

Hepatitis, Hepatitis A Virus, Immunization, Vaccination, hepatitis A vaccine, immunoglobulin G antibody, immunoglobulin M antibody, virus antibody, age distribution, article, child, controlled study, female, geographic distribution, hepatitis A, human, infant, lowest income group, major clinical study, male, mass immunization, onset age, preschool child, residential area, school child, seroprevalence, Turkey (republic)

Kaynak

Iranian Journal of Pediatrics

WoS Q Değeri

Scopus Q Değeri

Q3

Cilt

23

Sayı

3

Künye