Effects of moderate pressure distention on the proximal and distal sections of the saphenous vein

Basit Öğe Kaydı
dc.authorscopusid23391660500
dc.authorscopusid10139012600
dc.authorscopusid17134802600
dc.authorscopusid24069725600
dc.authorscopusid57000520600
dc.authorscopusid14008084500
dc.authorscopusid55317577700
dc.authorwosidgur, ozcan/AAA-8847-2022
dc.authorwosidGurkan, Selami/AAA-9006-2022
dc.contributor.authorYümün, Gündüz
dc.contributor.authorGür, Özcan
dc.contributor.authorGelincik, İbrahim
dc.contributor.authorAy, Derih
dc.contributor.authorDonbaloğlu, Mehmet Okan
dc.contributor.authorGürkan, Selami
dc.contributor.authorÖzkaramanlı Gür, Demet
dc.date.accessioned2022-05-11T14:10:05Z
dc.date.available2022-05-11T14:10:05Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kalp ve Damar Cerrahisi Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractStudies have shown that the distention and traction of a vein leads to the loss of cells and the function of the endothelia. Here, we aimed to compare the effects of pressure distention on the proximal and distal parts of the saphenous vein. Twenty patients were enrolled in this study. The proximal and distal saphenous vein segments were distended to three different pressure levels for two minutes: 100 mmHg, 200 mmHg, and 300 mmHg. In addition, the proximal and distal parts of the saphenous vein were compared with the immunohistochemical examinations and the organ bath system. The endothelial cell loss was similar in the proximal and distal segments at 300 mmHg. However, the endothelial cell loss rate was greater in the proximal segments than the distal segments at 100 mmHg and 200 mmHg (P=0.02 and P=0.06, respectively). The relaxation response of the proximal samples distended to 100 mmHg and 200 mmHg was significantly decreased when compared to the distal segment samples (P=0.049 and P=0.047, respectively). Furthermore, there was no relaxation response in the segment samples distended to 300 mmHg. While preparing the graft, inflations with pressures lower than 100 mmHg result in less endothelial damage, and are relatively protective on the graft functions. In this study, we have shown that the endothelial tissue of the distal saphenous vein is more resistant to moderate pressure.
dc.description.sponsorshipNamik Kemal University Research FundNamik Kemal University [20. AR.15.07]
dc.description.sponsorshipThis work was partly supported by Namik Kemal University Research Fund (Project no. 20. AR.15.07).
dc.identifier.endpage8365
dc.identifier.issn1936-2625
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-84994301744
dc.identifier.scopusqualityN/A
dc.identifier.startpage8359
dc.identifier.urihttps://hdl.handle.net/20.500.11776/5282
dc.identifier.volume9
dc.identifier.wosWOS:000386653400065
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYümün, Gündüz
dc.institutionauthorGür, Özcan
dc.institutionauthorGelincik, İbrahim
dc.institutionauthorDonbaloğlu, Mehmet Okan
dc.institutionauthorGürkan, Selami
dc.institutionauthorÖzkaramanlı Gür, Demet
dc.language.isoen
dc.publisherE-Century Publishing Corp
dc.relation.ispartofInternational Journal of Clinical and Experimental Pathology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectSaphenous vein
dc.subjectpressure
dc.subjectsegment
dc.subjectendothelial cell loss
dc.subjectrelaxation response
dc.subjectBypass-Surgery
dc.subjectGraft Failure
dc.subjectArtery
dc.titleEffects of moderate pressure distention on the proximal and distal sections of the saphenous vein
dc.typeArticle

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu