Recurrent squamous cell carcinoma of the skin treated successfully with single agent cetuximab therapy

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dc.authorid0000-0001-9081-2405
dc.authorid0000-0001-9081-2405
dc.authorscopusid6701472672
dc.authorscopusid56182776400
dc.authorscopusid57225369637
dc.authorscopusid8666331800
dc.authorwosidseber, selcuk/T-9539-2019
dc.authorwosidseber, selcuk e/H-3327-2017
dc.contributor.authorŞeber, Erdoğan Selçuk
dc.contributor.authorGönültaş, Aylin
dc.contributor.authorÖztürk, Özlem
dc.contributor.authorYetişyiğit, Tarkan
dc.date.accessioned2022-05-11T14:40:55Z
dc.date.available2022-05-11T14:40:55Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyasyon Onkolojisi Ana Bilim Dalı
dc.description.abstractRecurrent squamous cell carcinoma of the skin is a rare but difficult to treat condition. Frequently, the disease presents itself in elderly patients with poor performance status and bearing many comorbidities, thus the decision to administer systemic chemotherapy becomes difficult to make. In addition, current chemotherapeutic protocols response rates are far from satisfactory. Recently cetuximab, a chimeric antibody against epidermal growth factor receptor, is increasingly being reported as an alternative treatment. We therefore report this case of a recurrent squamous cell carcinoma of the skin in an elderly woman with poor performance status and who had an excellent clinical response to single agent cetuximab therapy with complete resolution of the disease and minimal toxicity during the course of the treatment to provide evidence for future prospective clinical trials.
dc.identifier.doi10.2147/OTT.S96227
dc.identifier.endpage948
dc.identifier.issn1178-6930
dc.identifier.pmid26955287
dc.identifier.scopus2-s2.0-84959356686
dc.identifier.scopusqualityQ2
dc.identifier.startpage945
dc.identifier.urihttps://doi.org/10.2147/OTT.S96227
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8974
dc.identifier.volume9
dc.identifier.wosWOS:000370980200001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorŞeber, Erdoğan Selçuk
dc.institutionauthorYetişyiğit, Tarkan
dc.language.isoen
dc.publisherDove Medical Press Ltd
dc.relation.ispartofOncotargets and Therapy
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcetuximab
dc.subjectEGFR inhibiton
dc.subjectsquamous cell carcinoma of the skin
dc.subjectCase Series
dc.subjectPhase-Ii
dc.subjectCancer
dc.subjectEgfr
dc.subjectChemotherapy
dc.subjectCisplatin
dc.subjectNeck
dc.subjectAcid
dc.subjectHead
dc.titleRecurrent squamous cell carcinoma of the skin treated successfully with single agent cetuximab therapy
dc.typeArticle

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