Inhalation and dermal exposure to atmospheric polycyclic aromatic hydrocarbons and associated carcinogenic risks in a relatively small city

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dc.authorid0000-0001-6990-0275
dc.authorscopusid56278323000
dc.authorscopusid7006990650
dc.authorscopusid6507872586
dc.authorscopusid6603671841
dc.authorwosidTECER, Lokman Hakan/ABA-7380-2020
dc.authorwosidSofuoglu, Sait C/A-6193-2018
dc.contributor.authorGungormus, Elif
dc.contributor.authorTuncel, Semra
dc.contributor.authorTecer, Lokman Hakan
dc.contributor.authorSofuoglu, Sait C.
dc.date.accessioned2022-05-11T14:17:15Z
dc.date.available2022-05-11T14:17:15Z
dc.date.issued2014
dc.departmentFakülteler, Çorlu Mühendislik Fakültesi, Çevre Mühendisliği Bölümü
dc.description.abstractThe aim of this study was to conduct a carcinogenic risk assessment for exposure to polycyclic aromatic hydrocarbons (PAHs) via routes of inhalation and dermal contact. Concentrations of 19 PAM species were determined during a heating period at a site in the city of Balikesir, Turkey. Two questionnaires were administered to a sample of inhabitants to determine time-activity budgets and demographic information. The assessment was conducted for each participant and Balikesir population by deterministic and probabilistic approaches, respectively. Monte Carlo simulation was implemented to determine the population exposure-risk probability distributions. The estimates were based on benzo[a]pyrene equivalent (BaPeq) total PAM concentrations calculated using toxic equivalency factors. The mean and median BaPeq concentrations of gaseous and particulate phases were 3.25 and 134, and 38.5 and 34.0 ng/m(3), respectively. Carcinogenic risk for inhalation exposure route was estimated by using two different slope factor values (3.9 and 304.5 (mg/kg-day)(-1)), recommended by two different organizations, resulting in two (order(s) of magnitude apart) population risk ranges: 1.32 x 10(-7)-2.23 x 10(-4), and 1.61 x 10(-5)-7.95 x 10(-3), respectively. The population risks associated with dermal exposure were lower compared to those of inhalation, ranging from 6.58 x 10(-9) to 2.57 x 10(-6). The proportion of the population with risks higher than the general acceptable level (1.0 x 10(-6)) was estimated as > 99 percent, for inhalation, and as 28 percent for dermal exposure route. (C) 2014 Elsevier Inc. All rights reserved.
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [108Y166]
dc.description.sponsorshipThis study was supported by a grant (108Y166) from the Scientific and Technological Research Council of Turkey (TUBITAK). The authors thank Emin Taylan of Middle East Technical University, Ankara, Turkey, for the analysis of the samples.
dc.identifier.doi10.1016/j.ecoenv.2014.06.015
dc.identifier.endpage113
dc.identifier.issn0147-6513
dc.identifier.issn1090-2414
dc.identifier.pmid25046852
dc.identifier.scopus2-s2.0-84904468189
dc.identifier.scopusqualityQ1
dc.identifier.startpage106
dc.identifier.urihttps://doi.org/10.1016/j.ecoenv.2014.06.015
dc.identifier.urihttps://hdl.handle.net/20.500.11776/6279
dc.identifier.volume108
dc.identifier.wosWOS:000342727800016
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorTecer, Lokman Hakan
dc.language.isoen
dc.publisherAcademic Press Inc Elsevier Science
dc.relation.ispartofEcotoxicology and Environmental Safety
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPolycyclic aromatic hydrocarbons
dc.subjectExposure
dc.subjectCarcinogenic risk
dc.subjectBalikesir
dc.subjectToxic Equivalency Factors
dc.subjectAir-Soil Exchange
dc.subjectDry Deposition
dc.subjectPahs
dc.subjectWeight
dc.subjectIndoor
dc.subjectRegion
dc.titleInhalation and dermal exposure to atmospheric polycyclic aromatic hydrocarbons and associated carcinogenic risks in a relatively small city
dc.typeArticle

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