What is the Effect of Pseudoexfoliation Syndrome on Renal Function in Patients without Glaucoma?
Loading...
Files
Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
Informa Healthcare
Access Rights
info:eu-repo/semantics/closedAccess
Abstract
Purpose: To evaluate renal function in patients with pseudoexfoliation syndrome. Materials and Methods: This prospective, cross-sectional, case-control study involved 49 patients with pseudoexfoliation syndrome (PEX) and 42 control subjects. Renal function was examined by biochemical parameters and Doppler ultrasonography. Serum creatinine, blood urea nitrogen, urea levels, urine microalbumin level and creatinine clearance were measured. Renal volume, resistive index and pulsatility index were calculated using Doppler ultrasonography. Results: The mean laboratory values for both groups were as follows: Creatinine, PEX: 0.81 +/- 0.28 mg/dL - Control: 0.79 +/- 0.22 mg/dL; urea, PEX: 31.6 +/- 9.7 mg/dL - Control: 32.2 +/- 8.4 mg/dL; blood urea nitrogen, PEX: 14.8 +/- 4.6 mg/dL - Control: 15.1 +/- 4.0 mg/dL; creatinine clearance, PEX: 89.1 +/- 35.6 mL/min - Control: 99.0 +/- 47.2 mL/min; microalbumin, PEX: 5.8 +/- 22.7 mg/dL - Control: 2.7 +/- 6.0 mg/dL. The differences between groups were not significant (p > 0.300). Renal volume, resistive index and pulsatility index values were similar in both groups (p > 0.200). Conclusions: This study showed that pseudoexfoliation syndrome does not affect biochemical and ultrasonographic parameters associated with renal function.
Description
Keywords
Biochemical parameters, blood-aqueous barrier, Doppler ultrasonography, glomerular filtration barrier, pseudoexfoliation syndrome, renal function, Blood-Aqueous Barrier, Resistive Index, Exfoliation Syndrome, Doppler Sonography, Pseudo-Exfoliation, Renovascular Resistance, Parenchymal Disease, Pulsatility Index, Kidney-Disease, Lens Capsule
Journal or Series
Current Eye Research
WoS Q Value
Q3
Scopus Q Value
Q2
Volume
39
Issue
2
