The fate of small side branches following drug eluting stent implantation

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dc.authorid0000-0001-7396-3818
dc.authorid0000-0002-2514-2991
dc.authorscopusid55317577700
dc.authorscopusid55929974600
dc.authorscopusid56667732600
dc.authorscopusid7003304689
dc.authorscopusid7003273404
dc.authorwosidErol, Cetin/AAS-8128-2020
dc.contributor.authorÖzkaramanlı Gür, Demet
dc.contributor.authorKumbasar, Deniz
dc.contributor.authorHural, Refika
dc.contributor.authorOral, Derviş
dc.contributor.authorErol, Çetin
dc.date.accessioned2022-05-11T14:40:09Z
dc.date.available2022-05-11T14:40:09Z
dc.date.issued2016
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractObjectives: Although drug eluting stents (DES) have documented convenience in bifurcation lesions, possible unfavorable effects on small side branch ostium(SBO) remain a question. We aimed to explore the effects of DES on small jailed SBs (1.5-2.25 mm) which originated from the lesion on the main vessel and were not treated with either stenting or balloon dilatation. Methods: Angiographic data of 107 consecutive patients (129 SB) with Medina 1,1,1 or 1,1,0 lesions were evaluated at the time of procedure and at the follow-up. Results: Of all DES used, 70 (54.7%) was sirolimus-eluting, 39 (30.5%) was paclitaxel-eluting and 20 (14.8%) was zotarolimus-eluting. The diameter of SBs was 1.84 +/- 0.41 mm with a stenosis of 20.7 +/- 26.6% at SBO at baseline. The lesion at the SBO had progressed after the procedure when the pre vs postprocedure values and follow-up vs pre-procedure values are compared (20.7 +/- 26.6% vs 29.4 +/- 27.4%; p < 0.0001 and 25.4 +/- 25.1 vs 20.7 +/- 26.6%; p = 0.004 respectively). A significant reduction in stenosis was revealed over the follow-up (29.4 +/- 27.4 vs 25.4 +/- 25.1 respectively; p = 0.013). The severity of the disease at the SBO at baseline was the only parameter that affected the severity of SB stenosis in acute, longterm and follow-up. Additional parameters with influence on SB patency at different times were female gender, stent deployment with low pressure, cTFC of the main lesion, age, cTFC of the lesion, late loss index and the preprocedure TIMI flow grade of the SB. Conclusions: Although there was a significant deterioration of SBO immediately after stenting, follow-up data showed that the lesion at SBO improved but remained worse than baseline. (C) 2016 The Authors. Published by Elsevier Ireland Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
dc.identifier.doi10.1016/j.ijcha.2016.06.001
dc.identifier.endpage37
dc.identifier.issn2352-9067
dc.identifier.pmid28616540
dc.identifier.scopus2-s2.0-84975311491
dc.identifier.scopusqualityQ2
dc.identifier.startpage34
dc.identifier.urihttps://doi.org/10.1016/j.ijcha.2016.06.001
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8881
dc.identifier.volume12
dc.identifier.wosWOS:000399040500007
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzkaramanlı Gür, Demet
dc.language.isoen
dc.publisherElsevier Ireland Ltd
dc.relation.ispartofIjc Heart & Vasculature
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDrug eluting stents
dc.subjectBifurcation lesions
dc.subjectSide branch
dc.subjectPercutaneous Coronary Intervention
dc.subjectBifurcation Lesions
dc.subjectClinical-Outcomes
dc.subjectOcclusion
dc.subjectPredictors
dc.titleThe fate of small side branches following drug eluting stent implantation
dc.typeArticle

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