Preparation of pH and temperature sensitive microspheres having magnetic properties and controlled drug delivery system
Yükleniyor...
Dosyalar
Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
IEEE
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, thermoresponsive hydrogel microspheres, namely, poly(N-isopropylacrylamide) (PNIPAAm) were prepared by using an inverse suspension polymerization technique. The radiation-induced modification of PNIPAAm microspheres with itaconic acid (IA) was applied for synthesizing pH and thermoresponsive PNIPAAm-co-poly(itaconic acid) microspheres (PNIPAAm-co-PIA). The PNIPAAM-co-PIA microspheres were simply immersed with iron (Fe2+, Fe3+) ions. In order to investigate drug release behavior of the prepared microspheres, 5-Fluorouracil as a model drug, namely, anti-cancer drug.
Açıklama
Scientific Meeting on Electric Electronics, Computer Science, Biomedical Engineerings (EBBT) -- APR 20-21, 2017 -- Istanbul Arel Univ, Istanbul, TURKEY
Anahtar Kelimeler
N-isopropylacrylamide, itaconic acid, magnetic, drug, drug, microsphere
Kaynak
2017 Electric Electronics, Computer Science, Biomedical Engineerings' Meeting (Ebbt)
WoS Q Değeri
N/A