Preparation of pH and temperature sensitive microspheres having magnetic properties and controlled drug delivery system

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Tarih

2017

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Yayıncı

IEEE

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

In this study, thermoresponsive hydrogel microspheres, namely, poly(N-isopropylacrylamide) (PNIPAAm) were prepared by using an inverse suspension polymerization technique. The radiation-induced modification of PNIPAAm microspheres with itaconic acid (IA) was applied for synthesizing pH and thermoresponsive PNIPAAm-co-poly(itaconic acid) microspheres (PNIPAAm-co-PIA). The PNIPAAM-co-PIA microspheres were simply immersed with iron (Fe2+, Fe3+) ions. In order to investigate drug release behavior of the prepared microspheres, 5-Fluorouracil as a model drug, namely, anti-cancer drug.

Açıklama

Scientific Meeting on Electric Electronics, Computer Science, Biomedical Engineerings (EBBT) -- APR 20-21, 2017 -- Istanbul Arel Univ, Istanbul, TURKEY

Anahtar Kelimeler

N-isopropylacrylamide, itaconic acid, magnetic, drug, drug, microsphere

Kaynak

2017 Electric Electronics, Computer Science, Biomedical Engineerings' Meeting (Ebbt)

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N/A

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