The place of infectious markers in predicting culture positivity in patients with renal failure hospitalized with suspected infection

Basit Öğe Kaydı
dc.authorscopusid8570900600
dc.authorscopusid57262368700
dc.authorscopusid34869282100
dc.authorscopusid55216749400
dc.authorscopusid6602163658
dc.contributor.authorÖzkan, Gülsüm
dc.contributor.authorÖzyılmaz, Semanur
dc.contributor.authorBayrakçı, Nergiz
dc.contributor.authorYıldırım, İlker
dc.contributor.authorErdem, İlknur
dc.date.accessioned2022-05-11T14:02:42Z
dc.date.available2022-05-11T14:02:42Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları Ana Bilim Dalı
dc.description.abstractInfectious diseases are an important cause of mortality in patients with renal failure. The markers used to diagnose infection in patients with renal failure have various limitations. Culture positivity is an objective guide in that context. The purpose of this study was to examine the effectiveness of frequently used markers of bacterial infection in predicting culture positivity in renal failure patients with renal failure hospitalized with suspected bacterial infection over an approximately 1.5-year period were included in this prospective observational study. Patients' demographic and laboratory findings were recorded. Demographic and laboratory findings and mortality were compared between patients with and without culture-positivity. Parameters affecting culture positivity were also analyzed. Four hundred twenty-six patients (median age 67.50, 45.5% female) were included in the study. Culture positivity was determined in 54.5% of patients. Hospital stay was longer (p < 0.001) and leukocyte (p < 0.001), neutrophil percentage (p < 0.05) and CRP (p < 0.001) values were significantly higher in culture-positive patients. Mortality was also significantly higher in culture-positive patients than in culture-negative patients (p < 0.05). CRP was determined as a predictor of culture positivity at logistic regression analysis (p = 0.000, exp ß [1.004]). Culture positivity was determined in more than half of the patients hospitalized with suspected bacterial infection. CRP, a longstanding marker, was identified as a parameter predicting culture positivity. We think that the determination in further studies of a cut-off point for CRP in determining culture positivity may be a useful diagnostic guide. © 2021 International Society for Apheresis, Japanese Society for Apheresis, and Japanese Society for Dialysis Therapy.
dc.identifier.doi10.1111/1744-9987.13731
dc.identifier.endpage336
dc.identifier.issn1744-9979
dc.identifier.issue2en_US
dc.identifier.pmid34494720
dc.identifier.scopus2-s2.0-85115052810
dc.identifier.scopusqualityQ2
dc.identifier.startpage330
dc.identifier.urihttps://doi.org/10.1111/1744-9987.13731
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4447
dc.identifier.volume26
dc.identifier.wosWOS:000696899700001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖzkan, Gülsüm
dc.institutionauthorÖzyılmaz, Semanur
dc.institutionauthorBayrakçı, Nergiz
dc.institutionauthorYıldırım, İlker
dc.institutionauthorErdem, İlknur
dc.language.isoen
dc.publisherJohn Wiley and Sons Inc
dc.relation.ispartofTherapeutic Apheresis and Dialysis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAKI
dc.subjectCKD
dc.subjectCRP
dc.subjectinfection
dc.subjectrenal failure
dc.subjectbiological marker
dc.subjectC reactive protein
dc.subjectbacterial infection
dc.subjectfemale
dc.subjecthuman
dc.subjectkidney failure
dc.subjectmale
dc.subjectneutrophil
dc.subjectprospective study
dc.subjectBacterial Infections
dc.subjectBiomarkers
dc.subjectC-Reactive Protein
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectNeutrophils
dc.subjectProspective Studies
dc.subjectRenal Insufficiency
dc.titleThe place of infectious markers in predicting culture positivity in patients with renal failure hospitalized with suspected infection
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim Yok
İsim:
4447.pdf
Boyut:
948.8 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu