Kliniğimizdeki oral glukoz tolerans testi (OGTT) bozukluğı olan gebelerde doğum ağırlığı ve doğum şekli arasındaki ilişki
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2022
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Tekirdağ Namık Kemal Üniversitesi
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info:eu-repo/semantics/openAccess
Özet
Bu çalışma Namık Kemal Üniversitesi Girişimsel olmayan klinik araştırmalar Etik Kurulunun 28.06.2022 tarihli ve 2022.118.06.08 protokol numaralı kararından sonra Helsinki deklorasyonu kuralları gözetilerek yapılmıştır. Ocak2018-Mart 2022 tarihleri arasında Tekirdağ Namık Kemal Üniversitesi Tıp Fakültesi Sağlık Uygulama m ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Gebe Polikliniğe gelen 24. ve 28. Gebelik haftalarındaki Oral Glükoz Tolerans Testi yapılması için başvuran toplam 128 hastadan OGTT yüksek olarak değerlendirilmiş 64 hasta ve Oral Glükoz Tolerans Testi normal gelmiş kontrol grupta olan 64 hasta dahil edilerek doğum şekli ve doğum ağırlığı arasında ilişkinin araştırılması için retrospektif yapılmış bir çalışmadır. Yapılmış çalışmada OGTT normal gelen grubun yaş ortalaması daha düşük iken, OGTT yüksek gelen grubun yaş ortalaması, daha yüksek olarak görüldü. Normal grubun doğum ağırlıkları arasında istatistiksel olarak anlamlı farklılık saptanmamıştır.Araştırmamızda OGTT yüksek gelmiş hastalarımızın uygun tedavi alıp-almamaları sorulmadığı için bu verilerin gelecekte yapılacak olan araştırmalarda tartışılması gerekmektedir.Normal grubun doğum haftaları ortalaması 38,37±2,74 hf iken, OGTT grubun ortalaması 37,24±2,75 hf olarak izledik. Gruplara göre doğum haftaları arasında istatistiksel olarak anlamlı farklılık saptanmıştır (p=0,022; p<0,05). OGTT grubun doğum haftaları, normal gruptan daha düşük olduğu izlendi.Ayrıntılı olarak incelendiğinde; doğum haftalarındaki 1 birimlik artış, OGTT riskini 1,132 katına düşürmekte olduğunu gördük.Gruplara göre doğum şekilleri arasında istatistiksel olarak anlamlı farklılık saptanmadığı izlendi..Doğum haftası ile doğum ağırlığı arasında pozitif yönlü istatistiksel olarak anlamlı iyi düzeyde ilişki saptandığı görüldü. (r=0,782; p<0,01)..Doğum ağırlığı ve doğum haftası ölçümleri OGTT varlığı için bağımsız risk faktörüdür..Gruplara göre doğum ağırlıkları arasında istatistiksel olarak anlamlı farklılık saptanmamıştır.
This study was conducted following the decision of the Namık Kemal University Non-interventional Clinical Research Ethics Committee, dated 28.06.2022 and protocol number 2022.118.06.08, in accordance with the Helsinki declaration rules. Between January 2018 and March 2022, 64 patients whose OGTT was evaluated as high out of 128 patients who applied to Tekirdağ Namık Kemal University Medical Faculty Health Practice and Research Hospital, Gynecology and Obstetrics Pregnancy Outpatient Clinic for Oral Glucose Tolerance Test at 24 and 28 weeks of gestation, and This is a retrospective study to investigate the relationship between delivery type and birth weight by including 64 patients in the control group with normal Oral Glucose Tolerance Test. In the previous study, while the mean age of the group with OGTT normal was lower, the mean age of the group with high OGTT was found to be higher. No statistically significant difference was found between the birth weights of the normal group. Since our patients with high OGTT were not asked whether they received appropriate treatment or not, these data should be discussed in future studies. While the average week of birth of the normal group was 38.37±2.74 weeks, the average of the OGTT group was We observed it as 37.24±2.75 weeks. A statistically significant difference was found between the weeks of birth according to the groups (p=0.022; p<0.05). It was observed that the birth weeks of the OGTT group were lower than the normal group. When examined in detail; We found that a 1-unit increase in the week of birth reduces the risk of OGTT by 1.132 times. It was observed that there was no statistically significant difference between the delivery types according to the groups. (r=0.782; p<0.01).. Birth weight and week of birth measurements are independent risk factors for the presence of OGTT. There was no statistically significant difference between birth weights according to groups.
This study was conducted following the decision of the Namık Kemal University Non-interventional Clinical Research Ethics Committee, dated 28.06.2022 and protocol number 2022.118.06.08, in accordance with the Helsinki declaration rules. Between January 2018 and March 2022, 64 patients whose OGTT was evaluated as high out of 128 patients who applied to Tekirdağ Namık Kemal University Medical Faculty Health Practice and Research Hospital, Gynecology and Obstetrics Pregnancy Outpatient Clinic for Oral Glucose Tolerance Test at 24 and 28 weeks of gestation, and This is a retrospective study to investigate the relationship between delivery type and birth weight by including 64 patients in the control group with normal Oral Glucose Tolerance Test. In the previous study, while the mean age of the group with OGTT normal was lower, the mean age of the group with high OGTT was found to be higher. No statistically significant difference was found between the birth weights of the normal group. Since our patients with high OGTT were not asked whether they received appropriate treatment or not, these data should be discussed in future studies. While the average week of birth of the normal group was 38.37±2.74 weeks, the average of the OGTT group was We observed it as 37.24±2.75 weeks. A statistically significant difference was found between the weeks of birth according to the groups (p=0.022; p<0.05). It was observed that the birth weeks of the OGTT group were lower than the normal group. When examined in detail; We found that a 1-unit increase in the week of birth reduces the risk of OGTT by 1.132 times. It was observed that there was no statistically significant difference between the delivery types according to the groups. (r=0.782; p<0.01).. Birth weight and week of birth measurements are independent risk factors for the presence of OGTT. There was no statistically significant difference between birth weights according to groups.
Açıklama
Anahtar Kelimeler
GDM,OGTT,Makrozomi, GDM,OGTT,Makrozomi, Kadın Hastalıkları ve Doğum, Obstetrics and Gynecology
