Relationship between plasma osmolality and neutrophil/lymphocyte ratio in heart failure with reduced ejection fraction

Basit Öğe Kaydı
dc.contributor.authorÖzkaramanlı Gür, Demet
dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorBaykız, Derya
dc.contributor.authorAkyüz, Aydın
dc.date.accessioned2023-05-06T17:23:33Z
dc.date.available2023-05-06T17:23:33Z
dc.date.issued2022
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractAim: Heart failure (HF), a progressive disease, is accompanied by chronic inflammation and changes in osmolality. The neutrophil-to-lymphocyte ratio (NLR) demonstrates a sys- temic inflammatory response in most diseases; however, the relationship between plasma osmolality and the systemic inflammatory response in HF patients is not yet clear. There- fore, we aimed to investigate the possible associations of NLR with plasma osmolality levels in patients with HF. Materials and Methods: The present study included 189 consecutive patients with chronic HF with an ejection fraction (EF) of <40%. They were classified into four groups based on admission plasma osmolality quartiles: hypo-osmolar (first quartile), normo- hypo-osmolar (second quartile), normo-hyperosmolar (third quartile), and hyperosmolar (fourth quartile). We evaluated the relationship between NLR, plasma osmolality, type-B natriuretic peptide (BNP), and the New York Heart Association (NYHA) functional class. Results: The hyperosmolar group had an increased NLR (p = 0.007). The presence of NYHA class 3–4 functional capacity, high-sensitivity C-reactive protein, and high osmo- lality were independent predictors of increased NLR. In correlation analysis, osmolality was significantly positively correlated with NLR (r = 0.201, p = 0.011). Conclusion: Higher NLR values may be associated with increased plasma osmolality, which may indicate an increased inflammatory status in the HF phenomenon.
dc.identifier.endpage783
dc.identifier.issn2636-7688
dc.identifier.issue8en_US
dc.identifier.startpage777
dc.identifier.trdizinid1126769
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1126769
dc.identifier.urihttps://hdl.handle.net/20.500.11776/12151
dc.identifier.volume29
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorÖzkaramanlı Gür, Demet
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorBaykız, Derya
dc.institutionauthorAkyüz, Aydın
dc.language.isoen
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.titleRelationship between plasma osmolality and neutrophil/lymphocyte ratio in heart failure with reduced ejection fraction
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
12151.pdf
Boyut:
714.61 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu