The effect of body mass index on oncological and surgical outcomes in patients undergoing radical cystectomy for bladder cancer: A multicentre study of the association of urooncology, Turkey

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dc.authorscopusid9278394100
dc.authorscopusid55766957300
dc.authorscopusid7003764995
dc.authorscopusid36151868000
dc.authorscopusid56845610800
dc.authorscopusid11240177700
dc.authorscopusid13805770800
dc.contributor.authorIzol, V.
dc.contributor.authorDeger, M.
dc.contributor.authorBaltaci, S.
dc.contributor.authorAkgül, Murat
dc.contributor.authorSelvi, İ.
dc.contributor.authorÖzden, E.
dc.date.accessioned2022-05-11T14:04:58Z
dc.date.available2022-05-11T14:04:58Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Üroloji Ana Bilim Dalı
dc.description.abstractObjective: We aimed to evaluate the effect of body mass index (BMI) on oncological and surgical outcomes in patients who underwent radical cystectomy (RC) for bladder cancer (BC). Materials and Methods: We retrospectively assessed data from patients who underwent RC with pelvic lymphadenectomy and urinary diversion for BC recorded in the bladder cancer database of the Urooncology Association, Turkey, between 2007 and 2019. Patients were stratified into three groups according to the BMI cut-off values recommended by the WHO; Group 1 (normal weight, <25 kg/m2), Group 2 (overweight, 25.0-29.9 kg/m2) and Group 3 (obese, ?30 kg/m2). Results: In all, 494 patients were included, of them 429 (86.8%) were men and 65 (13.2%) were women. The median follow-up was 24 months (12-132 months). At the time of surgery, the number of patients in groups 1, 2 and 3 were 202 (40.9%), 215 (43.5%) and 77 (15.6%), respectively. The mean operation time and time to postoperative oral feeding were longer and major complications were statistically higher in Group 3 compared to Groups 1 and 2 (P =.019, P <.001 and P =.025, respectively). Although the mean overall survival (OS), cancer-specific survival (CSS), recurrence-free survival (RFS) and metastasis-free survival (MFS) was shorter in cases with BMI ? 30 kg/m2 compared with other BMI groups, differences were not statistically significant (P =.532, P =.309, P =.751 and P =.213, respectively). Conclusion: Our study showed that although major complications are more common in obese patients, the increase in BMI does not reveal a significant negative effect on OS, CSS, RFS and MFS. © 2020 John Wiley & Sons Ltd
dc.description.sponsorshipWe thank Deniz Bolat for writing support.
dc.identifier.doi10.1111/ijcp.13750
dc.identifier.issn1368-5031
dc.identifier.issue3en_US
dc.identifier.pmid33090610
dc.identifier.scopus2-s2.0-85096699402
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1111/ijcp.13750
dc.identifier.urihttps://hdl.handle.net/20.500.11776/4850
dc.identifier.volume75
dc.identifier.wosWOS:000584433400001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAkgül, Murat
dc.language.isoen
dc.publisherJohn Wiley and Sons Inc
dc.relation.ispartofInternational Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectadult
dc.subjectArticle
dc.subjectbladder cancer
dc.subjectbody mass
dc.subjectcancer specific survival
dc.subjectcystectomy
dc.subjectfemale
dc.subjecthospital readmission
dc.subjecthuman
dc.subjectintestine motility
dc.subjectlength of stay
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmetastasis free survival
dc.subjectoperation duration
dc.subjectoutcome assessment
dc.subjectoverall survival
dc.subjectpelvis lymphadenectomy
dc.subjectperoperative complication
dc.subjectpopulation research
dc.subjectpostoperative period
dc.subjectrecurrence free survival
dc.subjectretrospective study
dc.subjecttreatment outcome
dc.subjectTurkey (republic)
dc.subjectadverse event
dc.subjectbladder tumor
dc.subjectbody mass
dc.subjectclinical trial
dc.subjectepidemiology
dc.subjectmulticenter study
dc.subjectturkey (bird)
dc.subjectBody Mass Index
dc.subjectCystectomy
dc.subjectFemale
dc.subjectHumans
dc.subjectMale
dc.subjectRetrospective Studies
dc.subjectTreatment Outcome
dc.subjectTurkey
dc.subjectUrinary Bladder Neoplasms
dc.titleThe effect of body mass index on oncological and surgical outcomes in patients undergoing radical cystectomy for bladder cancer: A multicentre study of the association of urooncology, Turkey
dc.typeArticle

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