Maximal Exercise-Corrected QT as a Predictor of Coronary Artery Disease: Comparison of Simpler Heart Rate Corrections

Basit Öğe Kaydı
dc.authorscopusid16315021800
dc.authorscopusid6505680586
dc.authorscopusid26532378600
dc.authorscopusid55810763400
dc.authorscopusid7005837198
dc.authorwosidAlpsoy, Seref/Z-1808-2018
dc.contributor.authorAkyüz, Aydın
dc.contributor.authorAlpsoy, Şeref
dc.contributor.authorAkkoyun, Dursun Çayan
dc.contributor.authorDeğirmenci, Hasan
dc.contributor.authorGüler, Niyazi
dc.date.accessioned2022-05-11T14:40:07Z
dc.date.available2022-05-11T14:40:07Z
dc.date.issued2013
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalı
dc.description.abstractBackground and Objectives: The relationship between QT prolongation and myocardial ischemia is widely known. Due to the limited value of ST depression, we aimed to evaluate, by using four simpler heart rate corrections (Bazett, Framingham, Fridericia and Hodges), the value of maximal exercise-QTc prolongation in the diagnosis of coronary artery disease (CAD) presence and severity. Subjects and Methods: We enrolled 234 subjects (mean age 57.3 +/- 9 years, 143 men) who had undergone exercise testing and coronary angiography due to a suspicion of CAD in the study. Evaluating CAD severity with Gensini scoring, the CAD group (n=122) and controls with non-CAD were compared in terms of corrected QT duration at maximal exercise. Results: Age, gender, hypertension, dyslipidemia, smoking, exercise duration, resting, and peak heart rate were similar between the two groups (all p>0.05). The CAD group had higher raw QT values than the controls {268 (169-438) vs. 240 (168-348), p<0.001}. Although Framingham QTc of >= 350 ms and Fridericia QTc of >= 340 ms were seen to be useful for the diagnosis of CAD, there was no additive diagnostic value of exercise QTc in addition to ST depression. Maximal exercise-QTc Bazett (r=0.163, p=0.01), Framingham (r=0.239, p=0.001), and Fridericia (r=0.206, p=0.001) equations were weakly positively correlated with Gensini scoring. Conclusion: The patients with CAD have longer QTc intervals at peak heart rates during exercise. This finding provides insufficient evidence to support routine incorporation of QTc at peak heart rates into exercise test interpretation.
dc.identifier.doi10.4070/kcj.2013.43.10.655
dc.identifier.endpage663
dc.identifier.issn1738-5520
dc.identifier.issn1738-5555
dc.identifier.issue10en_US
dc.identifier.pmid24255649
dc.identifier.scopus2-s2.0-84888877536
dc.identifier.scopusqualityQ2
dc.identifier.startpage655
dc.identifier.urihttps://doi.org/10.4070/kcj.2013.43.10.655
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8871
dc.identifier.volume43
dc.identifier.wosWOS:000342389500002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAkyüz, Aydın
dc.institutionauthorAlpsoy, Şeref
dc.institutionauthorAkkoyun, Dursun Çayan
dc.institutionauthorDeğirmenci, Hasan
dc.institutionauthorGüler, Niyazi
dc.language.isoen
dc.publisherKorean Soc Cardiology
dc.relation.ispartofKorean Circulation Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCoronary artery disease
dc.subjectCorrected QT
dc.subjectExercise test
dc.subjectMyocardial-Ischemia
dc.subjectSt-Segment
dc.subjectInterval
dc.subjectElectrocardiograms
dc.subjectDeterminants
dc.subjectArrhythmias
dc.subjectDepression
dc.subjectDispersion
dc.subjectFormulas
dc.subjectSystem
dc.titleMaximal Exercise-Corrected QT as a Predictor of Coronary Artery Disease: Comparison of Simpler Heart Rate Corrections
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
8871.pdf
Boyut:
781.01 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
Tıp Fakültesi Koleksiyonu