A synchronous occurrence of urothelial carcinoma with abundant myxoid stroma and inverted papilloma of the urinary bladder

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dc.authorid0000-0002-6396-3168
dc.authorscopusid8067129500
dc.authorscopusid26431693600
dc.authorscopusid15844109600
dc.authorscopusid8067130000
dc.contributor.authorBehzatoğlu, Kemal
dc.contributor.authorYıldız, Pelin
dc.contributor.authorÖznur, Meltem
dc.contributor.authorBozkurt, Erol Rüştü
dc.date.accessioned2022-05-11T14:36:54Z
dc.date.available2022-05-11T14:36:54Z
dc.date.issued2012
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalı
dc.description.abstractAbundant myxoid stroma rarely occurs in urothelial carcinomas, and may cause diagnostic challenges when cells with eosinophilic cytoplasm forming nests and cords in a myxoid background are seen, particularly in the absence of typical carcinomatous appearance. Microscopic examination of transurethral resection specimen of a 71-year-old male patient revealed non-cohesive oval or elongated tumor cells with eosinophilic cytoplasm arranged in cord-like filigree pattern in an abundant myxoid stroma. Immunohisto chemically the tumor was positive for cytokeratin 7, cytokeratin 20, and 34BE12. About 90 to 100% nuclear staining was observed with p63, p53, and Ki-67. A second neoplasm with a flat overlying urothelial epithelium and a complete inverted cellular growth pattern was also noted. The neoplasm exhibited less than 2% and 10% nuclear staining with Ki-67 and p53, respectively. Considering histological, histochemical, and immunohistochemical findings, a diagnosis of synchronous urothelial carcinoma with abundant myxoid stroma and inverted papilloma was made.
dc.identifier.doi10.4081/rt.2012.e45
dc.identifier.endpage147
dc.identifier.issn2036-3605
dc.identifier.issn2036-3613
dc.identifier.issue3en_US
dc.identifier.pmid23087801
dc.identifier.scopus2-s2.0-84866507197
dc.identifier.scopusqualityQ4
dc.identifier.startpage145
dc.identifier.urihttps://doi.org/10.4081/rt.2012.e45
dc.identifier.urihttps://hdl.handle.net/20.500.11776/8469
dc.identifier.volume4
dc.identifier.wosWOS:000219663300011
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorÖznur, Meltem
dc.language.isoen
dc.publisherPagepress Publ
dc.relation.ispartofRare Tumors
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjecturinary bladder
dc.subjecturothelial carcinoma
dc.subjecttransitional cell carcinoma
dc.subjectmyxoid
dc.subjectinverted papilloma
dc.titleA synchronous occurrence of urothelial carcinoma with abundant myxoid stroma and inverted papilloma of the urinary bladder
dc.typeArticle

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